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Gene Expression Data
Assay Details
Assay
Reference: J:72426 Cheng HJ, et al., Plexin-a3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections. Neuron. 2001 Oct 25;32(2):249-63
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7718990
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cranial nerve Present 6A
TS17: facial ganglion Present 6A
TS17: trigeminal ganglion Present 6A
Specimen 6B: embryonic day 10.5; Plxna3tm1Matl/? (more )
Note: Genetic background of specimen was either homozygous female or hemizygous male.
Structure Level Pattern Image Note
TS17: facial ganglion Present 6B
TS17: trigeminal ganglion Present 6B
TS17: cranial nerve Present Regionally restricted 6B Ophthalmic branch of trigeminal nerve is defasciculated.
Specimen 6C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trigeminal nerve ophthalmic division Present 6C
Specimen 6D: embryonic day 11.5; Plxna3tm1Matl/? (more )
Note: Genetic background of specimen was either homozygous female or hemizygous male.
Structure Level Pattern Image Note
TS19: trigeminal nerve ophthalmic division Present Regionally restricted 6D Ophthalmic branch of trigeminal nerve is defasciculated.
Specimen 6I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cranial ganglion Present 6I
TS17: cranial nerve Present 6I
Specimen 6I inset: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS20: trochlear nerve Present 6I inset
Specimen 6J: embryonic day 10.5; Plxna3tm1Matl/? (more )
Note: Genetic background of specimen was either homozygous female or hemizygous male.
Structure Level Pattern Image Note
TS17: cranial ganglion Present 6J Positions and projections of most identifiable cranial ganglia were normal compared to wild type.
TS17: cranial nerve Present 6J Positions and projections of most identifiable cranial ganglia were normal compared to wild type.
Specimen 6J inset: embryonic day 11.5; Plxna3tm1Matl/? (more )
Note: Genetic background of specimen was either homozygous female or hemizygous male.
Structure Level Pattern Image Note
TS20: trochlear nerve Present 6J inset Ganglion position and axonal projections of cranial nerves are apparently the same as in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory