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Gene Expression Data
Assay Details
Assay
Reference: J:353361 Yu H, et al., The homeodomain transcription factor Six3 regulates hypothalamic Pomc expression and its absence from POMC neurons induces hyperphagia and mild obesity in male mice. Mol Metab. 2024 Sep;87:101993
Assay type: RT-PCR
MGI Accession ID: MGI:7717801
Gene symbol: Six3
Gene name: sine oculis-related homeobox 3
Probe: Six3-pF, Six3-pR
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR.
Results
Image: S4_Six3 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Six3fl/fl P adult TS28: pituitary gland Present Not Specified; total RNA involves: 129S1/Sv Six3tm2Gco/Six3tm2GcoNot Specified
POMCSix3KO P adult TS28: pituitary gland Weak (a) Not Specified; total RNA involves: 129S1/Sv * FVB/N Six3tm2Gco/Six3tm2Gco, Tg(Pomc1-cre)16Lowl/0Not Specified Conditional mutant.
Notes:
(a) Expression significantly decreased compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory