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Gene Expression Data
Assay Details
Assay
Reference: J:155273 Teng GQ, et al., Homozygous missense N629D hERG (KCNH2) potassium channel mutation causes developmental defects in the right ventricle and its outflow tract and embryonic lethality. Circ Res. 2008 Dec 5;103(12):1483-91
Assay type: RNA in situ
MGI Accession ID: MGI:7716629
Gene symbol: Hand2
Gene name: heart and neural crest derivatives expressed 2
Results
Specimen 6 +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch Present 6_+/+ Substantial expression in branchial arches and outflow tract
TS15: outflow tract Present 6_+/+ Substantial expression in branchial arches and outflow tract
TS15: primitive ventricle Present Regionally restricted 6_+/+ Substantial expression in right ventricle. Less expression in left ventricle.

Specimen 6 N629D/N629D: embryonic day 9.5; Kcnh2tm1.1Hjd/Kcnh2tm1.1Hjd (more )
Structure Level Pattern Image Note
TS15: branchial arch Weak 6_N629D/N629D Expression dowregulated compared to wild type.
TS15: outflow tract Weak 6_N629D/N629D Expression dowregulated compared to wild type.
TS15: primitive ventricle Weak 6_N629D/N629D Expression dowregulated compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory