About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:235885 Chou SY, et al., CLIC4 regulates apical exocytosis and renal tube luminogenesis through retromer- and actin-mediated endocytic trafficking. Nat Commun. 2016 Jan 20;7:10412
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7714698
Gene symbol: Lrp2
Gene name: low density lipoprotein receptor-related protein 2
Antibody: anti-megalin
Detection system: Secondary antibody
Results
Specimen 2c: postnatal day 0 (more )
Note: Double labeled: red - Lrp2; green - Lotus tetragonolobus agglutinin.
Structure Level Pattern Image Note
TS27: renal proximal tubule Present 2c Expression is subluminal.
Specimen 2d: postnatal day 0; Clic4tm1.1Aidi/Clic4tm1.1Aidi (more )
Note: Double labeled: red - Lrp2; green - Lotus tetragonolobus agglutinin.
Structure Level Pattern Image Note
TS27: renal proximal tubule Present 2d In this mutant staining was displaced.
Specimen 3e: postnatal adult (more )
Structure Level Pattern Image Note
TS28: renal proximal tubule Present 3e Expression is in a lumen outlining pattern.
Specimen 3f: postnatal adult; Clic4tm1.1Aidi/Clic4tm1.1Aidi (more )
Structure Level Pattern Image Note
TS28: renal proximal tubule Weak 3f
Specimen S1f WT: embryonic day 15.0 (more )
Note: Double labeled: red - Lrp2; green - Lotus tetragonolobus agglutinin.
Structure Level Pattern Image Note
TS23: renal tubule Present S1f WT Merge , S1f WT Megalin
Specimen S1f KO: embryonic day 15.0; Clic4tm1.1Aidi/Clic4tm1.1Aidi (more )
Note: Double labeled: red - Lrp2; green - Lotus tetragonolobus agglutinin.
Structure Level Pattern Image Note
TS23: renal tubule Present S1f KO Merge , S1f KO Megalin In this mutant staining was displaced.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory