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Gene Expression Data
Assay Details
Assay
Reference: J:350008 Karwacki-Neisius V, et al., WNT signalling control by KDM5C during development affects cognition. Nature. 2024 Mar;627(8004):594-603
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7714680
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: anti-Tbr1 (AB10554)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1h WT: embryonic day 13.5 (more )
Note: Double labeled: red - Tbr1; blue - Hoechst.
Structure Level Pattern Image Note
TS21: cortical plate Present 1h WT TBR1
Specimen 1h KO: embryonic day 13.5; Kdm5ctm1.2Yshi/Y (more )
Note: Double labeled: red - Tbr1; blue - Hoechst.
Structure Level Pattern Image Note
TS21: cortical plate Present 1h KO TBR1 The number of expressing cells is significantly reduced in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory