Gene Expression Data
Assay Details
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Assay
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Reference:
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J:76941
Lagger G, et al., Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression. EMBO J. 2002 Jun 3;21(11):2672-81
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7713472
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Gene symbol:
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Hdac1
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Gene name:
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histone deacetylase 1
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Probe:
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Hdac1 probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
3A wt:
embryonic day 7.5
(more  )
Specimen
3A wt:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Formaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: ectoplacental cone |
Strong |
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3A wt
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Highly expressed in ectoplacental cone, extraembryonic ectoderm and embryonic ectoderm.
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| TS11: embryo ectoderm |
Strong |
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3A wt
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Highly expressed in ectoplacental cone, extraembryonic ectoderm and embryonic ectoderm.
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| TS11: extraembryonic ectoderm |
Strong |
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3A wt
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Highly expressed in ectoplacental cone, extraembryonic ectoderm and embryonic ectoderm.
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Specimen
3A -/-:
(close )
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Genetic Background:
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either: (involves: 129P2/OlaHsd * 129/Sv) or (involves: 129P2/OlaHsd * C57BL/6)
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Mutant Allele(s):
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Hdac1tm1Sei/Hdac1tm1Sei
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Formaldehyde
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Specimen
3B wt:
embryonic day 8.5
(more )
Specimen
3B wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Formaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: head |
Strong |
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3B wt
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Elevated levels of expression in headfold and neural fold.
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| TS13: neural fold |
Strong |
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3B wt
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Elevated levels of expression in headfold and neural fold.
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Specimen
3B -/-:
(close )
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Genetic Background:
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either: (involves: 129P2/OlaHsd * 129/Sv) or (involves: 129P2/OlaHsd * C57BL/6)
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Mutant Allele(s):
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Hdac1tm1Sei/Hdac1tm1Sei
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Formaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: embryo |
Absent |
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3B -/-
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Specimen
3C wt:
embryonic day 9.5
(more )
Specimen
3C wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Formaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: embryo |
Strong |
Regionally restricted |
3C wt
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Highly expressed throughout embryo except in the developing heart.
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| TS15: heart |
Absent |
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3C wt
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| TS15: branchial arch |
Strong |
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3C wt
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Pronounced expression in branchial arches and limb bud.
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| TS15: limb bud |
Strong |
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3C wt
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Pronounced expression in branchial arches and limb bud.
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Specimen
3C -/-:
(close )
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Genetic Background:
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either: (involves: 129P2/OlaHsd * 129/Sv) or (involves: 129P2/OlaHsd * C57BL/6)
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Mutant Allele(s):
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Hdac1tm1Sei/Hdac1tm1Sei
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Formaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: embryo |
Absent |
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3C -/-
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Analysis Tools