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Tg(F10-Proc)785Fjc
Transgene Detail
Summary
Symbol: Tg(F10-Proc)785Fjc
Name: transgene insertion 785, Francis J Castellino
MGI ID: MGI:7713362
Transgene: Tg(F10-Proc)785Fjc  Location: unknown  
Alliance: Tg(F10-Proc)785Fjc page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(F10-Proc)785Fjc expresses 1 gene
 
Tg(F10-Proc)785Fjc expression driven by 1 gene
 
Mutation detailsThe transgenic (Tg) allele incorporates: F7 (FVII; inactivated by a deletion in the promoter), the F7-F10 intergenic region, the F10 promoter, complete mouse Proc cDNA (mPC), SV40 poly A, and F10 exons 2-9 (not active). (J:99205, J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:99205 Lay AJ, et al., Mice with a severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities. J Clin Invest. 2005 Jun;115(6):1552-61
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory