About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:293992 Mancia Leon WR, et al., Clustered gamma-protocadherins regulate cortical interneuron programmed cell death. Elife. 2020 Jul 7;9:e55374
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7713332
Gene symbol: Vip
Gene name: vasoactive intestinal polypeptide
Antibody: Anti-VIP
Results
Specimen 2-S1A Gad2Cre;Ai14;WT: postnatal day 30; Gad2tm2(cre)Zjh/Gad2+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: primary visual cortex inhibitory interneuron Present Regionally restricted 2-S1A Gad2cre;Ai14;WT VIP A subset of cortical inhibitory neurons (derived fom the caudal ganglionic eminence) were stained.
Specimen 2-S1A Gad2Cre;Ai14;Pcdhgfcon3/+: postnatal day 30; Gad2tm2(cre)Zjh/Gad2+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Pcdhgtm2Xzw/Pcdhg+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: primary visual cortex inhibitory interneuron Present Regionally restricted 2-S1A Gad2cre;Ai14;Pcdhgfcon3/+ VIP A subset of cortical inhibitory neurons (derived fom the caudal ganglionic eminence) were stained.
Specimen 2-S1A Gad2Cre;Ai14;Pcdhgfcon3/fcon3: postnatal day 30; Gad2tm2(cre)Zjh/Gad2+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Pcdhgtm2Xzw/Pcdhgtm2Xzw (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: primary visual cortex inhibitory interneuron Present Regionally restricted 2-S1A Gad2cre;Ai14;Pcdhgfcon3/fcon3 VIP The density of cortical inhibitory neurons stained positive was significantly reduced in the visual cortex of homozygous Gad2<Cre>;Ai14;Pcdhg<fcon3/fcon3>.
Specimen 3-S1A Nkx2.1Cre;Ai14;WT: postnatal day 30; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Nkx2-1-cre)2Sand/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: primary visual cortex inhibitory interneuron Present Regionally restricted 3-S1A Nkx2.1cre;Ai14;WT VIP A subset of cortical inhibitory neurons (derived fom the caudal ganglionic eminence) were stained.
Specimen 3-S1A Nkx2.1Cre;Ai14;Pcdhgfcon3/+: postnatal day 30; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Pcdhgtm2Xzw/Pcdhg+, Tg(Nkx2-1-cre)2Sand/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: primary visual cortex inhibitory interneuron Present Regionally restricted 3-S1A Nkx2.1cre;Ai14;Pcdhgfcon3/+ VIP A subset of cortical inhibitory neurons (derived fom the caudal ganglionic eminence) were stained.
Specimen 3-S1A Nkx2.1Cre;Ai14;Pcdhgfcon3/fcon3: postnatal day 30; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Pcdhgtm2Xzw/Pcdhgtm2Xzw, Tg(Nkx2-1-cre)2Sand/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: primary visual cortex inhibitory interneuron Present Regionally restricted 3-S1A Nkx2.1cre;Ai14;Pcdhgfcon3/fcon3 VIP The density of cortical inhibitory neurons stained positive in the visual cortex of homozygous Nkx2.1<Cre>;Ai14;Pcdhg<fcon3/fcon3> was similar to that of control animals.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory