Gene Expression Data
Assay Details
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Assay
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Reference:
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J:74066
Fauchey V, et al., Dopamine control of striatal gene expression during development: relevance to knockout mice for the dopamine transporter. Eur J Neurosci. 2000 Sep;12(9):3415-25
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7713125
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Gene symbol:
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Drd3
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Gene name:
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dopamine receptor D3
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Probe:
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D3 probe
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
1C D3 DAT+/+:
embryonic day 13.0
(more  )
Specimen
1C D3 DAT+/+:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd
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Age:
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embryonic day 13.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: corpus striatum |
Present |
Regionally restricted |
1C D3 DAT+/+
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Expression in both genotypes from G13 to P2. Expression restricted to subventricular zone.
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Specimen
1C D3 DAT-/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Slc6a3tm1Mca/Slc6a3tm1Mca
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Age:
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embryonic day 13.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: corpus striatum |
Present |
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1C D3 DAT-/-
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Expression in both genotypes from G13 to P2.
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Specimen
D3 P2 DAT+/+:
postnatal day 2
(more )
Specimen
D3 P2 DAT+/+:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: corpus striatum |
Present |
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Expression in both genotypes from G13 to P2.
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Specimen
D3 P2 DAT-/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Slc6a3tm1Mca/Slc6a3tm1Mca
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: corpus striatum |
Present |
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Expression in both genotypes from G13 to P2.
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Specimen
D3 P7 DAT+/+:
postnatal day 7
(more )
Specimen
D3 P7 DAT+/+:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
D3 Adult DAT+/+:
postnatal adult
(more )
Specimen
D3 Adult DAT+/+:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
D3 Adult DAT-/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Slc6a3tm1Mca/Slc6a3tm1Mca
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: accumbens nucleus |
Present |
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Expression levels increased in nucleus accumbens and subventricular zone of caudate putamen compared to wild type.
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| TS28: caudate-putamen |
Present |
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Expression levels increased in nucleus accumbens and subventricular zone of caudate putamen compared to wild type.
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Analysis Tools