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Gene Expression Data
Assay Details
Assay
Reference: J:106811 Johnson EB, et al., Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. Hum Mol Genet. 2005 Nov 15;14(22):3523-38
Assay type: RNA in situ
MGI Accession ID: MGI:7712826
Gene symbol: Msx1
Gene name: msh homeobox 1
Probe: Msx1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 8C Forelimb WT: embryonic day 11.5 (more )
Note: Wild type was either +/+ or heterozygous.
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 8C F WT
Specimen 8C Hindlimb WT: embryonic day 11.5 (more )
Note: Wild type was either +/+ or heterozygous.
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 8C H WT
Specimen 8C Forelimb KO: embryonic day 11.5; Lrp4tm1Her/Lrp4tm1Her (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 8C F KO
TS19: hindlimb bud ectoderm Present Regionally restricted 8C F KO Expression is ventrally and dorsally broadened compared to wild-type.
Specimen 8C Hindlimb KO: embryonic day 11.5; Lrp4tm1Her/Lrp4tm1Her (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 8C H KO
TS19: hindlimb bud ectoderm Present Regionally restricted 8C H KO Expression is ventrally and dorsally broadened compared to wild-type.
Specimen 8D Forelimb WT: embryonic day 11.5 (more )
Note: Wild type was either +/+ or heterozygous.
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 8D F WT
Specimen 8D Hindlimb WT: embryonic day 11.5 (more )
Note: Wild type was either +/+ or heterozygous.
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 8D H WT
Specimen 8D Forelimb KO: embryonic day 11.5; Lrp4tm1Her/Lrp4tm1Her (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 8D F KO
TS19: forelimb bud ectoderm Present Regionally restricted 8D F KO Expression is ventrally and dorsally broadened compared to wild-type.
Specimen 8D Hindlimb KO: embryonic day 11.5; Lrp4tm1Her/Lrp4tm1Her (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 8D H KO
TS19: hindlimb bud ectoderm Present Regionally restricted 8D H KO Expression is ventrally and dorsally broadened compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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