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Gene Expression Data
Assay Details
Assay
Reference: J:269929 Elbert A, et al., CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons. J Neurosci. 2019 Jan 2;39(1):177-192
Assay type: RNA in situ
MGI Accession ID: MGI:7711342
Gene symbol: Lhx6
Gene name: LIM homeobox protein 6
Probe: Lhx6 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2B control: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present 2B control
Specimen 2B Ctcf Nes-Cre: embryonic day 13.5; Ctcftm2Gal/Ctcftm2Gal, Tg(Nes-cre)2472Pick/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present 2B cKO Decreased expression compared with the control. In a subset of embryos, the reduction in expression was restricted to the caudal region.
Specimen 2D Puma-/-: embryonic day 13.5; Bbc3tm1Ast/Bbc3tm1Ast (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present 2D Puma-/-
Specimen 2D Ctcf Nes-Cre;Puma-/-: embryonic day 13.5; Bbc3tm1Ast/Bbc3tm1Ast, Ctcftm2Gal/Ctcftm2Gal, Tg(Nes-cre)2472Pick/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present 2D cKO;Puma-/- Decreased expression compared with the control. Preventing apoptosis of cells via removal of PUMA/Bbc3 failed to rescue the change.
Specimen 2G control rostral: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: medial ganglionic eminence Present 2G-1
Specimen 2G Ctcf Nes-Cre rostral: embryonic day 12.5; Ctcftm2Gal/Ctcftm2Gal, Tg(Nes-cre)2472Pick/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: medial ganglionic eminence Present 2G-2 A subtle decrease compared with control.
Specimen 2G control caudal: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: medial ganglionic eminence Present 2G-3
Specimen 2G Ctcf Nes-Cre caudal: embryonic day 12.5; Ctcftm2Gal/Ctcftm2Gal, Tg(Nes-cre)2472Pick/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: medial ganglionic eminence Present 2G-4 A subtle decrease compared with control.
Specimen 5C control: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present 5C control
Specimen 5C Ctcf Nkx-Cre: embryonic day 13.5; Ctcftm2Gal/Ctcftm2Gal, Tg(Nkx2-1-cre)2Sand/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present 5C cKO Decreased expression compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory