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Gene Expression Data
Assay Details
Assay
Reference: J:57342 Nishino J, et al., GFR alpha3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion. Neuron. 1999 Aug;23(4):725-36
Assay type: RNA in situ
MGI Accession ID: MGI:7711127
Gene symbol: Ret
Gene name: ret proto-oncogene
Probe: Ret probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3J: postnatal day 1 (more )
Structure Cell Type Level Pattern Image Note
TS27: superior cervical ganglion neuron Strong Regionally restricted 3J Highly expressed in most neurons.
Specimen 3K: postnatal day 1; Gfra3tm1Hmd/Gfra3tm1Hmd (more )
Structure Level Pattern Image Note
TS27: superior cervical ganglion Weak 3K Expression markedly reduced compared to wild type.
Specimen 4D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cervical ganglion Strong Regionally restricted 4D Abundatnt expression in superior cervical ganglion.
Specimen 4H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: superior cervical ganglion Weak 4H Expression transiently downregulated at E14.5.
Specimen 4L: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: superior cervical ganglion Present 4L Expression apparent at E16.5, E18.5 and postnatal day 5.
Specimen 4P: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: superior cervical ganglion Present 4P Expression apparent at E16.5, E18.5 and postnatal day 5.
Specimen 4T: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: superior cervical ganglion Present 4T Expression apparent at E16.5, E18.5 and postnatal day 5.
Specimen 6A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: paravertebral ganglion Present Regionally restricted 6A Expression in developing superior cervical ganglion.
Specimen 6B: embryonic day 12.5 (more )
Note: Double labeled: blue - Ret; blue - Th (assay MGI:7711131).
Structure Level Pattern Image Note
TS20: cervical ganglion Present Regionally restricted 6B Expression in developing superior cervical ganglion.
Specimen 6D: embryonic day 11.5; Gfra3tm1Hmd/Gfra3tm1Hmd (more )
Structure Level Pattern Image Note
TS19: paravertebral ganglion Present Regionally restricted 6D Expression similar to that of wild type.
Specimen 6E: embryonic day 12.5; Gfra3tm1Hmd/Gfra3tm1Hmd (more )
Note: Double labeled: blue - Ret; blue - Th (assay MGI:7711131).
Structure Level Pattern Image Note
TS20: cervical ganglion Present Regionally restricted 6E Author report caudal shift in superior cervical ganglion at E12.5.
Specimen 7O: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: trigeminal ganglion Present 7O
Specimen 7P: postnatal day 7; Gfra3tm1Hmd/Gfra3tm1Hmd (more )
Structure Level Pattern Image Note
TS28: trigeminal ganglion Present 7P
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory