Slc18a2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:54931 Finotto S, et al., Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells. Development. 1999 Jul;126(13):2935-44
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7709688
Gene symbol:	Slc18a2
Gene name:	solute carrier family 18 (vesicular monoamine), member 2

Antibody:	anti-VMAT-2
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to Cy3

Results

Specimen E13.5 Wild-type: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: adrenal gland	Weak	Single cells		Expression detectable in a few cells at E13.5.

Specimen E18.5 Wild-type: embryonic day 18.5 (more

)
Note: Additional data presented in Table 2.

Structure	Cell Type	Level	Pattern	Image	Note
TS26: adrenal gland	chromaffin cell of adrenal gland	Weak	Regionally restricted		Expression in subpopulation of chromaffin cells.

Specimen GR-/-: embryonic day 18.5; Nr3c1^tm1Gsc/Nr3c1^tm1Gsc (more

)
Note: Authors do not indicate specific Nr3c1 mutant analyzed. Both mutants have been annotated.

Structure	Level	Pattern	Image	Note
TS26: adrenal gland	Weak	Regionally restricted		No difference in number of expressing cells compared to wild type.

Specimen GR-/-: embryonic day 18.5; Nr3c1^tm2.1Gsc/Nr3c1^tm2.1Gsc (more

)
Note: Authors do not indicate specific Nr3c1 mutant analyzed. Both mutants have been annotated.

Structure	Level	Pattern	Image	Note
TS26: adrenal gland	Weak	Regionally restricted		No difference in number of expressing cells compared to wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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