Gene Expression Data
Assay Details
Assay
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Reference:
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J:54931
Finotto S, et al., Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells. Development. 1999 Jul;126(13):2935-44
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7709682
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Gene symbol:
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Penk
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Gene name:
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preproenkephalin
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Antibody:
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anti-met-enkephalin
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to Cy3
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Results
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Specimen
Wild-type:
embryonic day 18.5
(more )
Note: Additional data presented in Table 2.
Specimen
Wild-type:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Additional data presented in Table 2.
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: adrenal medulla |
chromaffin cell of adrenal gland |
Weak |
Regionally restricted |
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Expression in sub-population of chromaffin cells.
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Specimen
GR-/-:
embryonic day 18.5; Nr3c1tm1Gsc/ Nr3c1tm1Gsc
(more )
Note: Authors do not indicate specific Nr3c1 mutant analyzed. Both mutants have been annotated.
Specimen
GR-/-:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Nr3c1tm1Gsc/Nr3c1tm1Gsc
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Authors do not indicate specific Nr3c1 mutant analyzed. Both mutants have been annotated.
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Structure |
Level |
Pattern |
Image |
Note |
TS26: adrenal medulla |
Present |
Regionally restricted |
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Expression qualitatively unaffected compared to wild type.
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Specimen
GR-/-:
embryonic day 18.5; Nr3c1tm2.1Gsc/ Nr3c1tm2.1Gsc
(more )
Note: Authors do not indicate specific Nr3c1 mutant analyzed. Both mutants have been annotated.
Specimen
GR-/-:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Nr3c1tm2.1Gsc/Nr3c1tm2.1Gsc
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Authors do not indicate specific Nr3c1 mutant analyzed. Both mutants have been annotated.
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: adrenal medulla |
Weak |
Regionally restricted |
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Expression qualitatively unaffected compared to wild type.
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