Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:54931
Finotto S, et al., Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells. Development. 1999 Jul;126(13):2935-44
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:7709674
|
|
Gene symbol:
|
Th
|
|
Gene name:
|
tyrosine hydroxylase
|
|
|
Results
|
Specimen
E13.5 wt not shown:
embryonic day 13.5
(more  )
Note: Additional data presented in Figs. 2 and 3.
Specimen
E13.5 wt not shown:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Additional data presented in Figs. 2 and 3.
|
| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS21: adrenal gland |
chromaffin cell of adrenal gland |
Present |
Regionally restricted |
|
Expression co-localized with Phox2a in chromaffin cells.
|
Specimen
E13.5 hypo/hypo not shown:
embryonic day 13.5; Nr3c1tm1Gsc/ Nr3c1tm1Gsc
(more )
Note: Data presented in Figs. 2 and 3.
Specimen
E13.5 hypo/hypo not shown:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Nr3c1tm1Gsc/Nr3c1tm1Gsc
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Data presented in Figs. 2 and 3.
|
Specimen
E15.5 wt not shown:
embryonic day 15.5
(more )
Note: Data presented in Fig. 3.
Specimen
E15.5 wt not shown:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 15.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Data presented in Fig. 3.
|
Specimen
E15.5 hypo/hypo not shown:
embryonic day 15.5; Nr3c1tm1Gsc/ Nr3c1tm1Gsc
(more )
Note: Data presented in Fig. 3.
Specimen
E15.5 hypo/hypo not shown:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Nr3c1tm1Gsc/Nr3c1tm1Gsc
|
|
Age:
|
embryonic day 15.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Data presented in Fig. 3.
|
Specimen
4A:
embryonic day 18.5
(more )
Note: Additional data presented in Fig. 2 and Table 2.
Specimen
4A:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Additional data presented in Fig. 2 and Table 2.
|
| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: adrenal gland |
chromaffin cell of adrenal gland |
Strong |
|
4A
|
Expression in all chromaffin cells, co-localized with Phox2a.
|
Specimen
4B:
embryonic day 18.5; Nr3c1tm1Gsc/ Nr3c1tm1Gsc
(more )
Note: Additional data presented in Fig. 2 and Table 2.
Specimen
4B:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Nr3c1tm1Gsc/Nr3c1tm1Gsc
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Additional data presented in Fig. 2 and Table 2.
|
| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: adrenal gland |
chromaffin cell of adrenal gland |
Strong |
|
4B
|
Expression in all chromaffin cells.
|
Specimen
4C:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Nr3c1tm2.1Gsc/Nr3c1tm2.1Gsc
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: adrenal gland |
chromaffin cell of adrenal gland |
Strong |
|
4C
|
Expression in all chromaffin cells.
|
Specimen
5 TH wt:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Nr3c1tm1Gsc/Nr3c1tm1Gsc
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
5 TH null/null:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Nr3c1tm2.1Gsc/Nr3c1tm2.1Gsc
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Analysis Tools