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Gene Expression Data
Assay Details
Assay
Reference: J:134998 Sarraj MA, et al., Differential expression of TGFBR3 (betaglycan) in mouse ovary and testis during gonadogenesis. Growth Factors. 2007 Oct;25(5):334-45
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7709390
Gene symbol: Tgfbr3
Gene name: transforming growth factor, beta receptor III
Antibody: anti-Tgfbr3 (AF-242-PB)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A: embryonic day 13.0 (more )
Structure Cell Type Level Pattern Image Note
TS21: coelomic epithelium of testis Present 2A
TS21: coelomic vessel Present 2A
TS21: interstitium of the testis Present 2A
TS21: peritubular myoid cell peritubular myoid cell Present 2A

Specimen 2B: embryonic day 13.0; Tgfbr3tm1Stv/Tgfbr3tm1Stv (more )
Structure Level Pattern Image Note
TS21: testis Absent 2B

Specimen 3A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: interstitium of the testis Present 3A
TS20: primary sex cord Absent 3A

Specimen 3B: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: interstitium of the testis Present 3B
TS21: peritubular myoid cell peritubular myoid cell Present 3B
TS21: primary sex cord Absent 3B

Specimen 3C: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: interstitium of the testis Present 3C
TS21: peritubular myoid cell peritubular myoid cell Present 3C
TS21: primary sex cord Absent 3C

Specimen 3D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: interstitium of the testis Present 3D
TS22: primary sex cord Absent 3D

Specimen 3E: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: interstitium of the testis Present 3E
TS24: peritubular myoid cell peritubular myoid cell Present 3E
TS24: seminiferous cord Absent 3E

Specimen 3G: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: Sertoli cell Sertoli cell Present 3G
TS27: spermatocyte Present 3G
TS27: spermatogonium Present 3G
TS27: interstitium of the testis Present Single cells 3G

Specimen 3H: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: Sertoli cell Sertoli cell Present 3H
TS27: spermatocyte Present 3H
TS27: spermatogonium Present 3H
TS27: interstitium of the testis Present Single cells 3H

Specimen 3I: postnatal day 10 (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 3I
TS28: spermatocyte Present 3I
TS28: spermatogonium Present 3I
TS28: interstitium of the testis Present Single cells 3I

Specimen 3J: postnatal day 15 (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 3J
TS28: spermatocyte Present 3J
TS28: spermatogonium Present 3J
TS28: interstitium of the testis Present Single cells 3J

Specimen 3K: postnatal day 15 (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 3K
TS28: spermatocyte Present 3K
TS28: spermatogonium Present 3K
TS28: Leydig cell Leydig cell Present 3K
TS28: rest of interstitium of the testis Present Single cells 3K

Specimen 3L: postnatal day 15 (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Weak 3L
TS28: spermatocyte Present 3L
TS28: spermatogonium Present 3L
TS28: interstitium of the testis Present Single cells 3L

Specimen 4A: embryonic day 12.0 (more )
Note: Double labeled: green - Tgfbr3; red - Ddx4 (assay MGI:7709395).
Structure Level Pattern Image Note
TS20: testis Present Single cells 4A , 4C Expression is in somatic cells in close association with germ cells.
TS20: germ cell of testis Absent 4A , 4C

Specimen 4D: embryonic day 14.5 (more )
Note: Double labeled: green - Tgfbr3; red - Ddx4 (assay MGI:7709395).
Structure Cell Type Level Pattern Image Note
TS22: peritubular myoid cell peritubular myoid cell Present 4D , 4F
TS22: interstitium of the testis Present 4D , 4F
TS22: germ cell of testis Absent 4F , 4D

Specimen 4G: embryonic day 14.5 (more )
Note: Double labeled: green - Tgfbr3; red - Cyp11a1 (assay MGI:7709396).
Structure Cell Type Level Pattern Image Note
TS22: Leydig cell Leydig cell Present 4I , 4G

Specimen 4J: postnatal day 0 (more )
Note: Double labeled: green - Tgfbr3; red - Ddx4 (assay MGI:7709395).
Structure Cell Type Level Pattern Image Note
TS27: Sertoli cell Sertoli cell Present 4L , 4J
TS27: germ cell of testis Present Single cells 4L , 4J

Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mesenchymal stroma of ovary Present Single cells 5A
TS20: germ cell of ovary Present Clusters 5A

Specimen 5B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesenchymal stroma of ovary Present Single cells 5B
TS21: premeiotic germ cell of ovary Present Clusters 5B

Specimen 5C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mesenchymal stroma of ovary Present Single cells 5C
TS22: premeiotic germ cell of ovary Present Clusters 5C

Specimen 5D: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: oocyte Present 5D
TS27: mesenchymal stroma of ovary Weak Single cells 5D

Specimen 5E: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: oocyte Present 5E
TS28: mesenchymal stroma of ovary Weak Single cells 5E
TS28: ovary follicle cell granulosa cell Absent 5E

Specimen 5G: postnatal day 8 (more )
Structure Cell Type Level Pattern Image Note
TS28: ovary growing follicle granulosa cell Present 5G Expression is in differentiating granulosa cells in growing follicles.
TS28: mesenchymal stroma of ovary Weak Single cells 5G

Specimen 5H: postnatal day 15 (more )
Structure Cell Type Level Pattern Image Note
TS28: ovary growing follicle granulosa cell Present 5H Expression is in differentiating granulosa cells in growing follicles.
TS28: follicle cell of preantral follicle granulosa cell Present 5H
TS28: follicle cell of primordial follicle granulosa cell Present 5H
TS28: follicle cell of secondary follicle granulosa cell Present 5H
TS28: oocyte of preantral follicle Present 5H
TS28: oocyte of primary follicle Present 5H
TS28: oocyte of secondary follicle Present 5H
TS28: mesenchymal stroma of ovary Weak Single cells 5H
TS28: ovary theca Trace 5H There is a discrepancy between the text and the table. The text states there is very little expression but the table states expression is absent.

Specimen 5I: postnatal day 30 (more )
Structure Cell Type Level Pattern Image Note
TS28: ovary growing follicle granulosa cell Present 5I Expression is in differentiating granulosa cells in growing follicles.
TS28: follicle cell of preantral follicle granulosa cell Present 5I
TS28: follicle cell of primordial follicle granulosa cell Present 5I
TS28: follicle cell of secondary follicle granulosa cell Present 5I
TS28: oocyte of preantral follicle Present 5I
TS28: oocyte of primary follicle Present 5I
TS28: oocyte of secondary follicle Present 5I
TS28: mesenchymal stroma of ovary Weak Single cells 5I
TS28: ovary theca Trace 5I

Specimen 6A: embryonic day 13.5 (more )
Note: Double labeled: green - Tgfbr3; red - Ddx4 (assay MGI:7709395).
Structure Level Pattern Image Note
TS21: germ cell of ovary Present Regionally restricted 6C , 6A Expression is in a subpopulation.
TS21: oocyte Present Regionally restricted 6C , 6A Expression is in a subpopulation.

Specimen 6D: embryonic day 14.5 (more )
Note: Double labeled: green - Tgfbr3; red - Ddx4 (assay MGI:7709395).
Structure Level Pattern Image Note
TS22: germ cell of ovary Present Regionally restricted 6F , 6D Expression is in a subpopulation.
TS22: oocyte Present Regionally restricted 6F , 6D Expression is in a subpopulation.

Specimen 6G: embryonic day 16.5 (more )
Note: Double labeled: green - Tgfbr3; red - Ddx4 (assay MGI:7709395).
Structure Level Pattern Image Note
TS24: germ cell of ovary Present Regionally restricted 6I , 6G Expression is in a subpopulation.
TS24: oocyte Present Regionally restricted 6I , 6G Expression is in a subpopulation.

Specimen 6J: postnatal day 0 (more )
Note: Double labeled: green - Tgfbr3; red - Ddx4 (assay MGI:7709395).
Structure Level Pattern Image Note
TS27: oocyte Present 6J , 6L Expression is in virtually all oocytes.

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: germ cell of ovary Present Regionally restricted Expression is in a subpopulation of oogonia and oocytes.

Specimen Table E12.5 male: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: Leydig cell Leydig cell Weak
TS20: peritubular myoid cell peritubular myoid cell Weak
TS20: Sertoli cell Sertoli cell Absent
TS20: germ cell of testis Absent

Specimen Table E12.5 female: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mesenchymal stroma of ovary Moderate
TS20: germ cell of ovary Weak

Specimen Table E13.5 male: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: Leydig cell Leydig cell Strong
TS21: peritubular myoid cell peritubular myoid cell Moderate
TS21: Sertoli cell Absent
TS21: germ cell of testis Absent

Specimen Table E13.5 female: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesenchymal stroma of ovary Moderate
TS21: oocyte Moderate

Specimen Table E14.5 male: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: Leydig cell Leydig cell Strong
TS22: peritubular myoid cell peritubular myoid cell Moderate
TS22: Sertoli cell Sertoli cell Absent
TS22: germ cell of testis Absent

Specimen Table E14.5 female: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mesenchymal stroma of ovary Moderate
TS22: oocyte Moderate

Specimen Table E16.5 male: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: Leydig cell Leydig cell Strong
TS24: peritubular myoid cell peritubular myoid cell Moderate
TS24: Sertoli cell Sertoli cell Absent
TS24: germ cell of testis Absent

Specimen Table E16.5 female: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mesenchymal stroma of ovary Moderate
TS24: oocyte Moderate

Specimen Table P0 male: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: Leydig cell Leydig cell Strong
TS27: Sertoli cell Sertoli cell Strong
TS27: germ cell of testis Moderate
TS27: peritubular myoid cell peritubular myoid cell Weak

Specimen Table P0 female: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: oocyte Strong
TS27: pre-granulosa cell Absent

Specimen Table P5 male: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Strong
TS28: Sertoli cell Sertoli cell Strong
TS28: germ cell of testis Moderate
TS28: peritubular myoid cell peritubular myoid cell Weak

Specimen Table P5 female: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: oocyte Strong
TS28: ovary follicle cell Weak
TS28: ovary theca Absent

Specimen Table P15 male: postnatal day 15 (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Strong
TS28: germ cell of testis Moderate
TS28: peritubular myoid cell peritubular myoid cell Weak
TS28: Sertoli cell Sertoli cell Weak

Specimen Table P15 female: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: oocyte Strong
TS28: ovary follicle cell Moderate
TS28: ovary theca Absent There is a discrepancy between the text and the table. The text states there is very little expression but the table states expression is absent.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory