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Gene Expression Data
Assay Details
Assay
Reference: J:51420 Sharma K, et al., LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Cell. 1998 Dec 11;95(6):817-28
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7709294
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-Islet1
Detection system: Secondary antibody
Results
Specimen 5c: embryonic day 13.5 (more )
Note: Double labeled: brown - Isl1; blue - Chat (assay MGI:7709298).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord cervical region motor neuron Present Regionally restricted 5c Co-expression with Chat RNA in motor neurons in wild type embryos.
TS21: spinal cord cervical region interneuron Present Regionally restricted 5c Expression in dorsal-medial interneurons.
Specimen 5d: embryonic day 13.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd, Lhx4tm1Ssp/Lhx4tm1Ssp (more )
Note: Double labeled: brown - Isl1; blue - Chat (assay MGI:7709298).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord cervical region interneuron Present 5d
TS21: spinal cord cervical region motor neuron Present 5d
Specimen 6e: embryonic day 10.5 (more )
Note: Double labeled: brown - Isl1; blue - Lhx4 (assay MGI:7709299).
Structure Level Pattern Image Note
TS17: future spinal cord Present 6e
Specimen 6f: embryonic day 13.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd, Lhx4tm1Ssp/Lhx4tm1Ssp (more )
Note: Double labeled: brown - Isl1; blue - Lhx4 (assay MGI:7709299).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord motor neuron Present Regionally restricted 6f Expression in intermedio-lateral column.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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