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Gene Expression Data
Assay Details
Assay
Reference: J:51420 Sharma K, et al., LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Cell. 1998 Dec 11;95(6):817-28
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7709292
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-Islet1
Detection system: Secondary antibody
Results
Specimen 5a: embryonic day 13.5 (more )
Note: C6-C8 level of spinal cord.
Structure Cell Type Level Pattern Image Note
TS21: spinal cord cervical region motor neuron Present Regionally restricted 5a Expression in motor neurons from ventral-medial to intermedio-lateral positions.
Specimen 5b: embryonic day 13.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd, Lhx4tm1Ssp/Lhx4tm1Ssp (more )
Note: C6-C8 level of spinal cord.
Structure Cell Type Level Pattern Image Note
TS21: spinal cord cervical region motor neuron Present Regionally restricted 5b Number of expressing cells similar to that of wild type.
TS21: spinal cord ventral horn Absent 5b Ventral horn devoid of expressing cells.
Specimen 5o: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: hindbrain motor neuron Present Regionally restricted 5o Expression in trigeminal motor neurons.
Specimen 5p: embryonic day 13.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd, Lhx4tm1Ssp/Lhx4tm1Ssp (more )
Structure Level Pattern Image Note
TS21: hindbrain Present Regionally restricted 5p Expression in trigeminal motor neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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