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Gene Expression Data
Assay Details
Assay
Reference: J:51420 Sharma K, et al., LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Cell. 1998 Dec 11;95(6):817-28
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7709287
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-Isl1/2
Detection system: Secondary antibody
Results
Specimen 2a: embryonic day 13.5 (more )
Note: Ventral horn of spinal cord. Double labeled: black - Isl1 and Isl2 (assay MGI:7709288).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord thoracic region motor neuron Present Regionally restricted 2a
Specimen 2b: embryonic day 13.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Note: Ventral horn of spinal cord. Double labeled: black - Isl1 and Isl2 (assay MGI:7709288).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord thoracic region motor neuron Present Regionally restricted 2b Expression in normal locations compared to wild type.
Specimen 2c: embryonic day 13.5 (more )
Note: Ventral horn of spinal cord. Double labeled: black - Isl1 and Isl2 (assay MGI:7709288).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord thoracic region motor neuron Present Regionally restricted 2c
Specimen 2d: embryonic day 13.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd, Lhx4tm1Ssp/Lhx4tm1Ssp (more )
Note: Ventral horn of spinal cord. Double labeled: black - Isl1 and Isl2 (assay MGI:7709288).
Structure Level Pattern Image Note
TS21: spinal cord thoracic region Absent 2d
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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