About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:316653 Chen Z, et al., Klf10 regulates odontoblast differentiation and mineralization via promoting expression of dentin matrix protein 1 and dentin sialophosphoprotein genes. Cell Tissue Res. 2016 Feb;363(2):385-98
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7707864
Gene symbol: Pcna
Gene name: proliferating cell nuclear antigen
Antibody: anti-PCNA
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen S1f/u: embryonic day 12.5 (more )
Note: Double labeled: green - Pcna; red - Klf10 (assay MGI:7707819).
Structure Level Pattern Image Note
TS20: tooth bud Present S1u , S1a/f Coexpressed with Klf10 in both the dental epithelium and the underlying mesenchyme.
Specimen S1g/v: embryonic day 16.5 (more )
Note: Double labeled: green - Pcna; red - Klf10 (assay MGI:7707819).
Structure Level Pattern Image Note
TS24: inner enamel epithelium Present S1b/g , S1v Coexpressed with Klf10.
TS24: outer enamel epithelium Present S1b/g , S1v Coexpressed with Klf10.
TS24: secondary enamel knot Present S1b/g , S1v Coexpressed with Klf10.
TS24: stratum intermedium Present S1b/g , S1v Coexpressed with Klf10.
TS24: molar mesenchyme Present Regionally restricted S1v , S1b/g Coexpressed with Klf10 in the mesenchymal cells beneath the inner enamel epithelia.
Specimen S1h/w: postnatal day 2 (more )
Note: Double labeled: green - Pcna; red - Klf10 (assay MGI:7707819).
Structure Cell Type Level Pattern Image Note
TS27: molar dental pulp odontoblast Present S1c/h , S1w Coexpressed with Klf10 in differentiating odontoblasts.
TS27: molar enamel organ ameloblast Present S1w , S1c/h Coexpressed with Klf10 in differentiating ameloblasts.
Specimen S1i/x: postnatal day 10 (more )
Note: Double labeled: green - Pcna; red - Klf10 (assay MGI:7707819).
Structure Cell Type Level Pattern Image Note
TS28: molar dental pulp odontoblast Present S1x , S1d/i Coexpressed with Klf10.
TS28: molar enamel organ ameloblast Present S1x , S1d/i Coexpressed with Klf10.
Specimen S1j/y: postnatal day 20 (more )
Note: Double labeled: green - Pcna; red - Klf10 (assay MGI:7707819).
Structure Cell Type Level Pattern Image Note
TS28: molar dental pulp odontoblast Present S1y , S1e/j Coexpressed with Klf10.
TS28: molar enamel organ ameloblast Present S1y , S1e/j Coexpressed with Klf10.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory