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Gene Expression Data
Assay Details
Assay
Reference: J:237482 Amandio AR, et al., Hotair Is Dispensible for Mouse Development. PLoS Genet. 2016 Dec;12(12):e1006232
Assay type: RNA in situ
MGI Accession ID: MGI:7707842
Gene symbol: Hoxd10
Gene name: homeobox D10
Probe: Hoxd10 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6B wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: paraxial mesenchyme Present Regionally restricted 6B wt Hoxd10 Rostral limits of expression were indicated.
TS20: spinal cord Present Regionally restricted 6B wt Hoxd10 Rostral limits of expression were indicated.
Specimen 6B Del(Hotair)-/-: embryonic day 12.5; Hotairtm1.1Hyc/Hotairtm1.1Hyc (more )
Structure Level Pattern Image Note
TS20: paraxial mesenchyme Present Regionally restricted 6B Del(Hotair)-/- Hoxd10 No detectable difference in the anterior limit of expression was observed in the mutant compared with wild type.
TS20: spinal cord Present Regionally restricted 6B Del(Hotair)-/- Hoxd10 No detectable difference in the anterior limit of expression was observed in the mutant compared with wild type.
Specimen 6C wt Hoxd10;MyoD: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: paraxial mesenchyme Present Regionally restricted 6C wt Hoxd10;MyoD Expression was detected in the future spine up to the level of somite 26.
TS20: spinal cord Present Regionally restricted 6C wt Hoxd10;MyoD Expression was detected in the future spine up to the level of somite 26.
Specimen 6C Del(Hotair)-/- Hoxd10;MyoD: embryonic day 12.5; Hotairtm1.1Hyc/Hotairtm1.1Hyc (more )
Structure Level Pattern Image Note
TS20: paraxial mesenchyme Present Regionally restricted 6C Del(Hotair)-/- Hoxd10;MyoD No detectable difference in the anterior limit, intensity of the signal, or the spatial pattern of expression was observed in the mutant compared with wild type.
TS20: spinal cord Present Regionally restricted 6C Del(Hotair)-/- Hoxd10;MyoD No detectable difference in the anterior limit, intensity of the signal, or the spatial pattern of expression was observed in the mutant compared with wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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