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Gene Expression Data
Assay Details
Assay
Reference: J:76140 Shibata S, et al., In situ hybridization and immunohistochemistry of bone sialoprotein and secreted phosphoprotein 1 (osteopontin) in the developing mouse mandibular condylar cartilage compared with limb bud cartilage. J Anat. 2002 Mar;200(Pt 3):309-20
Assay type: RNA in situ
MGI Accession ID: MGI:7707666
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Probe: Col10a1 cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tibia-fibula pre-cartilage condensation Absent 1D Expression not detected at this stage.

Specimen 2F: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: tibia cartilage condensation chondrocyte Present Regionally restricted 2F Expression in chondrocytes of entire hypertrophic cell zone.

Specimen 3D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epiphyseal plate hypertrophic zone Present Regionally restricted 3D Expression in peripheral part of hypertrophic cell zone corresponding to upper hypertrophic cell zone. Expression less extensive in lower hypertrophic cell zone.
TS23: tibia epiphysis Present Regionally restricted 3D Expression in peripheral part of hypertrophic cell zone corresponding to upper hypertrophic cell zone. Expression less extensive in lower hypertrophic cell zone.

Specimen 4D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mandible Absent 4D No expression in bone tissue.
TS22: mandible condylar condensation Absent 4D No expression in condylar anlage.

Specimen 5D: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: mandible condylar process chondrocyte Present Widespread 5D Widely expressed in newly formed chondrocytes.

Specimen 6D: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: mandible condylar process chondrocyte Present Regionally restricted 6D Expression in chondrocytes of upper hypertrophic zone. Weak expression in lower hypertrophic zone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory