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Gene Expression Data
Assay Details
Assay
Reference: J:73310 Sowden JC, et al., Expression of Drosophila omb-Related T-Box Genes in the Developing Human and Mouse Neural Retina. Invest Ophthalmol Vis Sci. 2001 Dec;42(13):3095-102
Assay type: RNA in situ
MGI Accession ID: MGI:7707443
Gene symbol: Tbx2
Gene name: T-box 2
Probe: Tbx2 probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 3D Expression in dorsal hemisphere of optic cup. Expression domain
TS17: 1st branchial arch mandibular component Present 3D Expression in maxillary process and mandibular process.
TS17: 1st branchial arch maxillary component Present 3D Expression in maxillary process and mandibular process.
Specimen 4B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: retina Present Regionally restricted 4B Abundant expression throughout dorsal retinal hemisphere.
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: retina Present Regionally restricted No expression in ventral retina.
Specimen 4E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: neural retina Present Regionally restricted 4E At level of optic nerve, expression concentrated in inner neuroblastic layer of dorsal retinal hemisphere.
TS22: cornea Present 4E
TS22: mesenchyme derived from neural crest Present Regionally restricted 4E Expression in overlying neural crest-derived mesenchyme giving rise to anterior segment of eye.
Specimen 4H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: neural retina Present Regionally restricted 4H Dorsally, expression restricted to inner neuroblastic layer of dorsal retinal hemisphere.
TS22: cornea Present 4H Expression in developing cornea.
TS22: mesenchyme derived from neural crest Present Regionally restricted 4H Expression in overlying neural crest-derived mesenchyme giving rise to anterior segment of eye.
Specimen 4K: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 4K No expression in ventral retinal hemisphere.
TS22: cornea Present 4K
TS22: mesenchyme derived from neural crest Present Regionally restricted 4K Expression in overlying neural crest-derived mesenchyme giving rise to anterior segment of eye.
Specimen 4L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: upper eyelid mesenchyme Present 4L
Specimen 4O: postnatal adult (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present 4O Expression most abundant within inner nuclear layer and ganglion cell layer.
TS28: retina inner nuclear layer Present 4O Expression most abundant within inner nuclear layer and ganglion cell layer.
TS28: photoreceptor layer Absent 4O
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory