Gene Expression Data
Assay Details
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Assay
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Reference:
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J:250104
Flodby P, et al., The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development. Am J Respir Cell Mol Biol. 2016 Jul;55(1):135-49
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7705090
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Gene symbol:
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Casp3
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Gene name:
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caspase 3
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Results
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Specimen
6C:
(close  )
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Genetic Background:
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involves: 129 * C57BL/6 * DBA/2
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Mutant Allele(s):
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Hspa5tm1Alee/Hspa5tm1Alee
Tg(Sftpc-cre)1Blh/0
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Conditional mutant. Double labeled: green - Casp3; red - Nkx2-1 (assay MGI:7704205).
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: lung epithelium |
pulmonary alveolar type 2 cell |
Present |
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6C left
,
6C middle
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Colocalization of cleaved caspase 3 and Nkx2-1 in cells detaching from the epithelial layer was seen.
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| TS26: lung |
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Present |
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6C left
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6C middle
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Most of the positive cells located in airspaces.
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Analysis Tools
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