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Gene Expression Data
Assay Details
Assay
Reference: J:250104 Flodby P, et al., The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development. Am J Respir Cell Mol Biol. 2016 Jul;55(1):135-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7705089
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175) (#9661)
Detection system: Secondary antibody
Results
Specimen 6B f/f E14: embryonic day 14.0; Hspa5tm1Alee/Hspa5tm1Alee (more )
Structure Level Pattern Image Note
TS22: lung Trace Single cells 6B E14 f/f
Specimen 6B cKO E14: embryonic day 14.0; Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: lung Trace Single cells 6B E14 cKO Similar as in the controls.
Specimen 6B f/f E18: embryonic day 18.0; Hspa5tm1Alee/Hspa5tm1Alee (more )
Structure Level Pattern Image Note
TS26: lung Trace Single cells 6B E18 f/f
Specimen 6B cKO E18: embryonic day 18.0; Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: lung Present 6B E18 cKO Increased positive cells located in distal airspaces, but not bronchiolar epithelial cells.
Specimen E6 f/f: embryonic day 18.0; Hspa5tm1Alee/Hspa5tm1Alee (more )
Structure Level Pattern Image Note
TS26: lung Trace Single cells E6_f/f
Specimen E6 cKO: embryonic day 18.0; Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: lung Present E6_cKO Increased positive cells located in distal airspaces, but not bronchiolar epithelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory