Gene Expression Data
Assay Details
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Assay
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Reference:
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J:111429
Feng JQ, et al., Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res. 2002 Oct;17(10):1822-31
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7705074
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Gene symbol:
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Dmp1
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Gene name:
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dentin matrix protein 1
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Probe:
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Dmp1 probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
1A Dmp1:
embryonic day 12.5
(more  )
Specimen
1A Dmp1:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: embryo |
Absent |
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1A Dmp1
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Expression virtually undetectable.
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Specimen
1B Dmp1:
embryonic day 14.5
(more )
Specimen
1B Dmp1:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: embryo |
Present |
Regionally restricted |
1B Dmp1 inset
,
1B Dmp1
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Expression in developing skeleton confined to areas containing hypertrophic cartilage.
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Specimen
1C Dmp1:
embryonic day 16.5
(more )
Specimen
1C Dmp1:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: embryo |
Present |
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1C Dmp1
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Specimen
1d1:
embryonic day 16.5
(more )
Specimen
1d1:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1d2:
embryonic day 16.5
(more )
Specimen
1d2:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1d3 upper:
embryonic day 16.5
(more )
Specimen
1d3 upper:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1d3 lower left:
embryonic day 16.5
(more )
Specimen
1d3 lower left:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: rib |
Present |
Regionally restricted |
1d3 lower left
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No expression in areas of cartilage not undergoing mineratization.
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Specimen
1d3 lower right:
embryonic day 16.5
(more )
Specimen
1d3 lower right:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5C Wt:
embryonic day 16.5
(more )
Specimen
5C Wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: femur |
Strong |
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5C Wt
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Specimen
5C Cbfa1-/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: femur |
Absent |
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5C Cbfa1-/-
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No expression in developing bones.
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Specimen
5D Wt:
embryonic day 16.5
(more )
Specimen
5D Wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: tooth |
Strong |
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5D Wt
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Highly expressed in developing teeth.
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Specimen
5D Cbfa1-/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: tooth |
Strong |
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5D Cbfa1-/-
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Expression in the arrested tooth bud similar to that of normal tooth.
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Specimen
5E Wt:
embryonic day 19.5
(more )
Specimen
5E Wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 19.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: tooth |
Strong |
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5E Wt
,
5E Wt inset
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Highly expressed in developing teeth.
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Specimen
5E Cbfa1-/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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embryonic day 19.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: tooth |
Strong |
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5E Cbfa1-/- inset
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5E Cbfa1-/-
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Expression in the arrested tooth bud similar to that of normal tooth.
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Specimen
6c:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: epiphyseal plate hypertrophic zone |
Strong |
Regionally restricted |
6c
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Highly expressed in newly formed hypertrophic cartilage formation in primary ossification center of diaphysis.
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Specimen
6c1:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
6d:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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embryonic day 18.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
6d1:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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embryonic day 18.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
6e:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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postnatal week 8
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: femur |
Present |
Regionally restricted |
6e
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Expression in advanced mineralization of diaphysis with formation of osteocyte lacunae.
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Specimen
6e1:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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postnatal week 8
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
6e2:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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postnatal week 8
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: femur |
osteocyte |
Strong |
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6e2
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High expression in osteocytes embedded in bone matrix.
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Specimen
7B left:
postnatal week 2
(more )
Specimen
7B left:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 2
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
7B middle:
postnatal week 2
(more )
Specimen
7B middle:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 2
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
7B right:
postnatal week 2
(more )
Specimen
7B right:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 2
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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