Runx2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:111429 Feng JQ, et al., Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res. 2002 Oct;17(10):1822-31
Assay type:	RNA in situ
MGI Accession ID:	MGI:7705073
Gene symbol:	Runx2
Gene name:	runt related transcription factor 2

Probe:	Cbfa1 probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

Specimen 1A Cbfa1: embryonic day 12.5 (more

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Structure	Level	Pattern	Image	Note
TS20: cartilage condensation	Strong		1A Cbfa1	Highly expressed in developing cartilage tissues.

Specimen 1B Cbfa1: embryonic day 14.5 (more

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Structure	Level	Pattern	Image	Note
TS22: cartilage condensation	Strong		1B Cbfa1	High level of expression in cartilaginous tissues.

Specimen 1C Cbfa1: embryonic day 16.5 (more

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Structure	Level	Pattern	Image	Note
TS24: embryo	Present	Regionally restricted	1C Cbfa1

Specimen 1D1: embryonic day 16.5 (more

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Structure	Cell Type	Level	Pattern	Image	Note
TS24: chondrocranium	hypertrophic chondrocyte	Present		1D1

Specimen 1D2: embryonic day 16.5 (more

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Structure	Cell Type	Level	Pattern	Image	Note
TS24: vertebra	osteoblast	Present		1D2

Specimen 1D3 upper: embryonic day 16.5 (more

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Structure	Cell Type	Level	Pattern	Image	Note
TS24: rib	hypertrophic chondrocyte	Present		1D3 upper

Specimen 1D3 lower left: embryonic day 16.5 (more

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Structure	Level	Pattern	Image	Note
TS24: rib	Present	Regionally restricted	1D3 lower left	Expression in areas of cartilage not undergoing mineratization.

Specimen 1D3 lower right: embryonic day 16.5 (more

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Structure	Cell Type	Level	Pattern	Image	Note
TS24: rib	hypertrophic chondrocyte	Present		1D3 lower right

Specimen 7A left: postnatal week 2 (more

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Structure	Level	Pattern	Image	Note
TS28: femur	Absent		7A left	Expression virtually undetectable.

Specimen 7A middle: postnatal week 2 (more

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Structure	Level	Pattern	Image	Note
TS28: bone	Absent		7A middle	Expression virtually undetectable.

Specimen 7A right: postnatal week 2 (more

)

Structure	Level	Pattern	Image	Note
TS28: cartilage	Absent		7A right	Expression virtually undetectable.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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