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Gene Expression Data
Assay Details
Assay
Reference: J:250104 Flodby P, et al., The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development. Am J Respir Cell Mol Biol. 2016 Jul;55(1):135-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7704223
Gene symbol: P4hb
Gene name: prolyl 4-hydroxylase, beta polypeptide
Antibody: anti-PDI (ADI-SPA-890)
Detection system: Secondary antibody
Results
Specimen 4H f/f: embryonic day 18.0; Hspa5tm1Alee/Hspa5tm1Alee (more )
Structure Cell Type Level Pattern Image Note
TS26: terminal bronchiole epithelium epithelial cell of lung Present 4 cont_H f/f Expressed in epithelial cells lining the saccules in distal lung.
Specimen 4H cKO: embryonic day 18.0; Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: terminal bronchiole epithelium epithelial cell of lung Strong 4 cont_H cKO Increased expression in epithelial cells lining the saccules in distal lung compared with the controls.
Specimen E5B f/f: embryonic day 18.0; Hspa5tm1Alee/Hspa5tm1Alee (more )
Structure Cell Type Level Pattern Image Note
TS26: lung epithelium epithelial cell of lung Present E5B f/f
Specimen E5B cKO: embryonic day 18.0; Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: lung epithelium pulmonary alveolar epithelial cell Present Regionally restricted E5B cKO Increased expression in alveolar epithelial cells, but not in bronchiolar epithelial cells in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory