Gt(ROSA)26Sortm2(CAG-LOC4337827)Afst
Targeted Allele Detail
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| Symbol: |
Gt(ROSA)26Sortm2(CAG-LOC4337827)Afst |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 2, A Francis Stewart |
| MGI ID: |
MGI:7703953 |
| Synonyms: |
Rosa26Tir1 |
| Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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| Alliance: |
Gt(ROSA)26Sortm2(CAG-LOC4337827)Afst page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:353472
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| Parent Cell Line: |
E14TG2a (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The target vector was designed to insert a CMV-IE enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter (CAG), an Oryza sativa F-box transport inhibitor response 1 (TIR1) sequence, linked to an N-terminal nuclear localization signal (NLS), an internal ribosome entry site (IRES) sequence and a puromycin cassette, into intron 1 of the Gt(ROSA)26Sor locus.
(J:353473)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gt(ROSA)26Sor Mutation: |
1042 strains or lines available
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| Original: |
J:353472 Fedl AS, et al., Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development. Nat Immunol. 2024 Sep;25(9):1663-1677 |
| All: |
2 reference(s) |
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Analysis Tools
