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Gene Expression Data
Assay Details
Assay
Reference: J:68750 Cacalano G, et al., GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney. Neuron. 1998 Jul;21(1):53-62
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7703381
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-tyrosine hydroxylase
Detection system: horseradish peroxidase
Results
Specimen 2A: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: substantia nigra dopaminergic neuron Present 2A

Specimen 2B: postnatal day 0; Gfra1tm1Rosl/Gfra1tm1Rosl (more )
Structure Cell Type Level Pattern Image Note
TS27: substantia nigra dopaminergic neuron Present 2B Normal complement of dopaminergic neurons.

Specimen 2C: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: corpus striatum dopaminergic neuron Present 2C

Specimen 2D: postnatal day 0; Gfra1tm1Rosl/Gfra1tm1Rosl (more )
Structure Cell Type Level Pattern Image Note
TS27: corpus striatum dopaminergic neuron Present 2D No significant reduction in density of dopaminergic projections.

Specimen 2E: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: locus coeruleus noradrenergic neuron Present 2E

Specimen 2F: postnatal day 0; Gfra1tm1Rosl/Gfra1tm1Rosl (more )
Structure Cell Type Level Pattern Image Note
TS27: locus coeruleus noradrenergic neuron Present 2F Normal number of noradrenergic neurons.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory