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Gene Expression Data
Assay Details
Assay
Reference: J:46668 Ma Q, et al., neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia. Neuron. 1998 Mar;20(3):469-82
Assay type: RNA in situ
MGI Accession ID: MGI:7703211
Gene symbol: Nhlh1
Gene name: nescient helix loop helix 1
Probe: Nscl cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Two probes were described, but the one used in this assay was not detailed. Nscl cDNA3 MGI:5569545 may have been used in this assay.
Results
Specimen 4E: embryonic day 8.75 (more )
Note: 20 somites.
Structure Level Pattern Image Note
TS13: trigeminal placode Absent 4E Stage just before expression is detected in trigeminal placode.
Specimen 4F: embryonic day 9.0 (more )
Note: 22 somites.
Structure Level Pattern Image Note
TS14: trigeminal placode Strong 4F Strong expression in trigeminal placode.
Specimen 5C: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: geniculate placode Present 5C
TS14: otic placode Present 5C
TS14: petrosal placode Present 5C
TS14: trigeminal placode Present 5C
TS14: epibranchial placode Present Regionally restricted 5C Expression in nodose (X) placode.
Specimen 5D: embryonic day 9.0; Neurog1tm1And/Neurog1tm1And (more )
Structure Level Pattern Image Note
TS14: otic placode Absent 5D Expression compltetely lost in otic and trigeminal placode.
TS14: trigeminal placode Absent 5D Expression compltetely lost in otic and trigeminal placode.
TS14: geniculate placode Present 5D Expression in geniculate (VII) and petrosal (IX) placodes unaffected compared to wild type.
TS14: petrosal placode Present 5D Expression in geniculate (VII) and petrosal (IX) placodes unaffected compared to wild type.
TS14: epibranchial placode Present Regionally restricted 5D Expression in nodose (X) placode unaffected compared to wild type.
Specimen +/+ not shown: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: migrating neural crest Present
Specimen -/- not shown: embryonic day 10.0; Neurog1tm1And/Neurog1tm1And (more )
Structure Level Pattern Image Note
TS16: migrating neural crest Absent No expression in migrating neural crest cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory