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Gene Expression Data
Assay Details
Assay
Reference: J:341382 Wu B, et al., Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 Sep 19;12(18):e029683
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7666671
Gene symbol: Eln
Gene name: elastin
Results
Specimen 5B E10.5: embryonic day 10.5 (more )
Structure Cell Type Level Pattern Image Note
TS17: atrioventricular endocardial cushion cardiac mesenchymal cell Absent 5B E10.5
TS17: atrioventricular endocardial cushion endocardial cell Absent 5B E10.5
Specimen 5B E11.5: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: atrioventricular endocardial cushion cardiac mesenchymal cell Absent 5B E11.5
TS19: atrioventricular endocardial cushion endocardial cell Absent 5B E11.5
Specimen 5B E12.5: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: atrioventricular endocardial cushion cardiac mesenchymal cell Absent 5B E12.5
TS20: atrioventricular endocardial cushion endocardial cell Absent 5B E12.5
Specimen 5B E13.5: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: atrioventricular valve cardiac mesenchymal cell Present 5B E13.5
Specimen 5B E14.5: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: atrioventricular valve cardiac mesenchymal cell Strong 5B E14.5
Specimen 5B E15.5: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: atrioventricular valve cardiac mesenchymal cell Strong 5B E15.5
Specimen 5B E16.5: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: atrioventricular valve cardiac mesenchymal cell Strong 5B E16.5
Specimen 6D Control: embryonic day 13.5; Crktm1Cur/Crktm1Cur, Crkltm1Cur/Crkltm1Cur (more )
Structure Level Pattern Image Note
TS21: atrioventricular endocardial cushion Present Regionally restricted 6D Control Expression was detected in distinct fibrous networks in the remodeling atrioventricular valves.
Specimen 6D DKO: embryonic day 13.5; Crktm1Cur/Crktm1Cur, Crkltm1Cur/Crkltm1Cur, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: atrioventricular endocardial cushion Present Regionally restricted 6D DKO Immunostaining showed dysregulated deposition of Eln.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory