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Rbm4bem1Wtarn
Endonuclease-mediated Allele Detail
Summary
Symbol: Rbm4bem1Wtarn
Name: RNA binding motif protein 4B; endonuclease-mediated mutation 1, Woan-Yuh Tarn
MGI ID: MGI:7666670
Gene: Rbm4b  Location: Chr19:4806480-4816199 bp, + strand  Genetic Position: Chr19, 4.11 cM
Alliance: Rbm4bem1Wtarn page
Mutation
origin
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready)
Mutation:    Insertion
 
Mutation details: Using the CRISPR/Cas9 technology, loxP-EcoRI sequence was inserted into intron 1 of Rbm4b in homozyogouse Rbm4tm1Wtarn embryo. (J:340400)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rbm4b Mutation:  16 strains or lines available
References
Original:  J:340400 Tsai YY, et al., Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency. Commun Biol. 2023 Sep 5;6(1):910
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory