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Gene Expression Data
Assay Details
Assay
Reference: J:46667 Fode C, et al., The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Neuron. 1998 Mar;20(3):483-94
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7666606
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: petrosal placode Absent

Specimen 3A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 3A Expression in anlagen of 3 distal cranial ganglia.
TS15: glossopharyngeal preganglion Present 3A Expression in anlagen of 3 distal cranial ganglia.
TS15: vagus preganglion Present Regionally restricted 3A Expression in nerve root of nodose ganglion.
TS15: trigeminal preganglion Present 3A

Specimen 3A': embryonic day 9.5; Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Absent 3A' Expression missing in regions of geniculate and petrosal ganglia.
TS15: glossopharyngeal preganglion Absent 3A' Expression missing in regions of geniculate and petrosal ganglia.
TS15: vagus preganglion Present 3A' Expression detected in nodose ganglion.
TS15: trigeminal preganglion Present 3A' Expression not affected by mutation.

Specimen 9A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: facial ganglion Absent 9A
TS17: glossopharyngeal ganglion Absent 9A
TS17: vagus ganglion Absent 9A

Specimen 9A': embryonic day 10.5; Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Structure Level Pattern Image Note
TS17: facial ganglion Absent 9A' Distal geniculate (VII) and petrosal (IX), ganglia are absent.
TS17: glossopharyngeal ganglion Absent 9A' Distal geniculate (VII) and petrosal (IX), ganglia are absent.
TS17: cranial nerve Present Regionally restricted 9A' Truncated motor root of cranial never VII and IXth nerve not obsesrved.
TS17: vagus ganglion Present 9A' Proximal cranial ganglia and Xth cranial nerve appear unaffected by mutation.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory