Ret RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:46667 Fode C, et al., The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Neuron. 1998 Mar;20(3):483-94
Assay type:	RNA in situ
MGI Accession ID:	MGI:7666589
Gene symbol:	Ret
Gene name:	ret proto-oncogene

Probe:	pmcRet7
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

Specimen 4C: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: facial ganglion	Present		4C	Expression in geniculate ganglion,

Specimen 4C': embryonic day 12.5; Neurog2^tm1Fgu/Neurog2^tm1Fgu (more

)

Structure	Level	Pattern	Image	Note
TS20: facial ganglion	Present		4C'	Expression in geniculate ganglion similar to that of wild type.

Specimen 8A: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: facio-acoustic preganglion complex	Present	Regionally restricted	8A	Exprswsion in distal geniculate (VII), petrosal (IX) and nodose (X) ganglia.
TS15: glossopharyngeal preganglion	Present	Regionally restricted	8A	Exprswsion in distal geniculate (VII), petrosal (IX) and nodose (X) ganglia.
TS15: vagus preganglion	Present	Regionally restricted	8A	Exprswsion in distal geniculate (VII), petrosal (IX) and nodose (X) ganglia.

Specimen 8A': embryonic day 9.5; Neurog2^tm1Fgu/Neurog2^tm1Fgu (more

)

Structure	Level	Image	Note
TS15: facio-acoustic preganglion complex	Absent	8A'	Expression not maintained in geniculate or petrosal precursors.
TS15: glossopharyngeal preganglion	Absent	8A'	Expression not maintained in geniculate or petrosal precursors.
TS15: vagus preganglion	Present	8A'	Expression only in nodose ganglion.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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