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Rr493 Other Genome Feature Detail
Summary
  • Symbol
    Rr493
  • Name
    regulatory region 493
  • Synonyms
    Pen, Pitx1-RA5
  • Feature Type
    enhancer
  • IDs
    MGI:7666385
  • Cluster Member
    Rr480652 (1 member)
  • Regulates expression of
    Pitx1 (1 regulated gene)
Location &
Maps
more
  • Sequence Map
    Chr13:56306831-56309000 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • J:268374: chr13:56260379-56262548 (mm9) chr13:56306831-56309000 (GRCm39)
  • Genetic Map
    Chromosome 13, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    163 from dbSNP Build 142
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
References
more
  • Summaries
    All 4
    Phenotypes 3
  • Earliest
    J:268374 Kragesteen BK, et al., Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis. Nat Genet. 2018 Oct;50(10):1463-1473
  • Latest
    J:369576 Bompadre O, et al., Liebenberg syndrome severity arises from variations in Pitx1 locus topology and proportion of ectopically transcribing cells. Nat Commun. 2025 Jul 9;16(1):6321
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory