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Gene Expression Data
Assay Details
Assay
Reference: J:85827 Shintani T, et al., Neurons as well as astrocytes express proteoglycan-type protein tyrosine phosphatase zeta/RPTPbeta: analysis of mice in which the PTPzeta/RPTPbeta gene was replaced with the LacZ gene. Neurosci Lett. 1998 May 15;247(2-3):135-8
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7663978
Gene symbol: Ptprz1
Gene name: protein tyrosine phosphatase receptor type Z, polypeptide 1
Reporter: lacZ
Direct Detection
Results
Specimen 1D: embryonic day 8.5; Ptprz1tm1Mno/Ptprz1+ (more )
Note: Fixative was 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS13: future prosencephalon Present 1D
TS13: neural fold Present 1D

Specimen 1E: embryonic day 12.5; Ptprz1tm1Mno/Ptprz1+ (more )
Note: Fixative was 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS20: forebrain Present 1E
TS20: hindbrain Present 1E
TS20: midbrain Present 1E
TS20: spinal cord Present 1E

Specimen 3A: postnatal day 10; Ptprz1tm1Mno/Ptprz1+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 3A
TS28: cerebral cortex Present 3A
TS28: hippocampus Present 3A
TS28: main olfactory bulb Present 3A
TS28: medulla oblongata Present 3A
TS28: superior colliculus Present 3A
TS28: thalamus Present 3A

Specimen 3B: postnatal day 7; Ptprz1tm1Mno/Ptprz1+ (more )
Structure Cell Type Level Pattern Image Note
TS28: cortical layer II cerebral cortex pyramidal neuron Present Regionally restricted 3B Expression is in subsets of neurons including pyramidal neurons.
TS28: cortical layer II neuron Present Regionally restricted 3B Expression is in subsets of neurons including pyramidal neurons.
TS28: cortical layer III cerebral cortex pyramidal neuron Present Regionally restricted 3B Expression is in subsets of neurons including pyramidal neurons.
TS28: cortical layer III neuron Present Regionally restricted 3B Expression is in subsets of neurons including pyramidal neurons.
TS28: cortical layer V cerebral cortex pyramidal neuron Present Regionally restricted 3B Expression is in subsets of neurons including pyramidal neurons.
TS28: cortical layer V neuron Present Regionally restricted 3B Expression is in subsets of neurons including pyramidal neurons.

Specimen 3C: postnatal day 10; Ptprz1tm1Mno/Ptprz1+ (more )
Note: Double labeled: blue - Ptprz1 reporter; brown - Gfap (assay MGI:7663979).
Structure Cell Type Level Pattern Image Note
TS28: hippocampus astrocyte Present 3C

Specimen 3D: postnatal adult; Ptprz1tm1Mno/Ptprz1+ (more )
Structure Cell Type Level Pattern Image Note
TS28: hippocampus hippocampal pyramidal neuron Strong 3D
TS28: dentate gyrus granule cell layer Strong 3D

Specimen not shown: postnatal adult; Ptprz1tm1Mno/Ptprz1+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Present
TS28: cerebral cortex Present
TS28: hippocampus Present
TS28: main olfactory bulb Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory