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Gene Expression Data
Assay Details
Assay
Reference: J:123400 Mitchell DC, et al., Developmental expression of three small GTPases in the mouse eye. Mol Vis. 2007;13:1144-53
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7662347
Gene symbol: Rhoa
Gene name: ras homolog family member A
Antibody: anti-RhoA
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 1A: embryonic day 11.5 (more )
Note: Tissues were fixed in zinc-formalin fixative.
Structure Level Pattern Image Note
TS19: cornea Strong 1A RhoA
TS19: lens vesicle Strong 1A RhoA
TS19: retina Strong 1A RhoA
Specimen 1B: embryonic day 14.5 (more )
Note: Tissues were fixed in zinc-formalin fixative.
Structure Level Pattern Image Note
TS22: cornea Present 1B RhoA
TS22: lens epithelium Present 1B RhoA
TS22: lens fiber Present 1B RhoA
TS22: retina layer Present Regionally restricted 1B RhoA Expression is in the inner region of the neuroblastic layer.
TS22: pigmented retinal epithelium Weak 1B RhoA
Specimen 1C: embryonic day 17.5 (more )
Note: Tissues were fixed in zinc-formalin fixative.
Structure Level Pattern Image Note
TS25: lens fiber Strong Non-Uniform 1C RhoA Expression is the epithelial and primary fiber cells and to a lesser degree in the cortical fiber cells.
TS25: cornea epithelium Present 1C RhoA
TS25: lens epithelium Present 1C RhoA
TS25: pigmented retinal epithelium Present 1C RhoA
TS25: cornea Present Regionally restricted 1C RhoA Expression is in corneal endothelial cells.
TS25: retina layer Present Regionally restricted 1C RhoA Expression is in the photoreceptor and pigment layers of the retina.
Specimen 2A: postnatal day 1 (more )
Note: Tissues were fixed in zinc-formalin fixative.
Structure Level Pattern Image Note
TS27: lens epithelium Strong 2A
TS27: photoreceptor layer Strong 2A
TS27: retina layer Strong Regionally restricted 2A Expression is in horizontal/amacrine/Muller cell layers.
TS27: retina ganglion cell layer Strong Single cells 2A Expression is in some ganglion cells and is lower in other ganglion cells.
TS27: cornea endothelium Present 2A
TS27: lens fiber Present 2A
TS27: cornea stroma Present Regionally restricted 2A Expression is in some stromal fibroblasts.
TS27: cornea epithelium Weak 2A
TS27: retina inner plexiform layer Weak 2A
TS27: retina outer plexiform layer Weak 2A
Specimen 3A: postnatal month 2 (more )
Note: Tissues were fixed in zinc-formalin fixative.
Structure Level Pattern Image Note
TS28: lens Absent 3A RhoA
Specimen 3B: postnatal month 2 (more )
Note: Tissues were fixed in zinc-formalin fixative.
Structure Level Pattern Image Note
TS28: cornea endothelium Strong Regionally restricted 3B RhoA Expression is in the top layer.
TS28: cornea epithelium Strong Regionally restricted 3B RhoA Expression is in the top layer.
TS28: cornea stroma Strong Regionally restricted 3B RhoA Expression is in the bodies of some fibroblasts.
Specimen 3C: postnatal month 2 (more )
Note: Tissues were fixed in zinc-formalin fixative.
Structure Level Pattern Image Note
TS28: photoreceptor layer Strong 3C RhoA
TS28: retina layer Strong Regionally restricted 3C RhoA Expression is in horizontal/amacrine/Muller cell layers.
TS28: retina ganglion cell layer Strong Single cells 3C RhoA Expression is in some ganglion cells
TS28: retina inner plexiform layer Weak 3C RhoA
TS28: retina outer plexiform layer Weak 3C RhoA
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory