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Gene Expression Data
Assay Details
Assay
Reference: J:132058 Bermingham-McDonogh O, et al., Expression of Prox1 during mouse cochlear development. J Comp Neurol. 2006 May 10;496(2):172-86
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7645525
Gene symbol: Prox1
Gene name: prospero homeobox 1
Results
Specimen 11A: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti Deiter's cell Present Regionally restricted 11A In basal region, reduction in nuclear expression in inner pillar cells and first an second rows of Deiters' cells, relative to outer pillar cells and third row of Deiters' cells.
TS27: organ of Corti external pillar cell of cochlea Present Regionally restricted 11A In basal region, reduction in nuclear expression in inner pillar cells and first an second rows of Deiters' cells, relative to outer pillar cells and third row of Deiters' cells.
TS27: organ of Corti internal pillar cell of cochlea Present Regionally restricted 11A In basal region, reduction in nuclear expression in inner pillar cells and first an second rows of Deiters' cells, relative to outer pillar cells and third row of Deiters' cells.

Specimen 11B: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti internal pillar cell of cochlea Weak Regionally restricted 11B In middle region, expression only reduced in inner pilar cell nuclei.

Specimen 11C: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti organ of Corti supporting cell Present Regionally restricted 11C In apical region, expression in all rows of support cell nuclei.

Specimen 11D: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted 11D In basal region, expression similar to that seen at P3.

Specimen 11E: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti Deiter's cell Weak Regionally restricted 11E In middle region of cochlea, expression clearly reduced in subsets of support cells, particularly those in first and second rows of Deiters' cells and outer pillar cells.
TS28: organ of Corti external pillar cell of cochlea Weak Regionally restricted 11E In middle region of cochlea, expression clearly reduced in subsets of support cells, particularly those in first and second rows of Deiters' cells and outer pillar cells.

Specimen 11F: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti internal pillar cell of cochlea Present Regionally restricted 11F In apical region of cochlea, more nuclei of inner pillar cells retain strong expression than in middle region.

Specimen 11G: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted 11G Expression not detectable in basal region.

Specimen 11H: postnatal day 10 (more )
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti Deiter's cell Weak Regionally restricted 11H Expression highly attentuated in middle region. Expression only detectable in nuclei of outer pillar cells and third row of Deiters' cells.
TS28: organ of Corti external pillar cell of cochlea Weak Regionally restricted 11H Expression highly attentuated in middle region. Expression only detectable in nuclei of outer pillar cells and third row of Deiters' cells.

Specimen 11I: postnatal day 10 (more )
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti Deiter's cell Present Regionally restricted 11I Expression highly attentuated in apical region. Expression only detectable in nuclei of outer pillar cells and third row of Deiters' cells.
TS28: organ of Corti internal pillar cell of cochlea Present Regionally restricted 11I Expression highly attentuated in apical region. Expression only detectable in nuclei of outer pillar cells and third row of Deiters' cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory