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Gene Expression Data
Assay Details
Assay
Reference: J:60196 Nokelainen P, et al., Expression of mouse 17beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase type 7 in the ovary, uterus, and placenta: localization from implantation to late pregnancy. Endocrinology. 2000 Feb;141(2):772-8
Assay type: RNA in situ
MGI Accession ID: MGI:7643979
Gene symbol: Hsd17b7
Gene name: hydroxysteroid (17-beta) dehydrogenase 7
Probe: m17HSD/KSR7 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A: postnatal adult (more )
Note: nonpregnant
Structure Level Pattern Image Note
TS28: corpus luteum Strong 1A

Specimen 1D: postnatal adult (more )
Note: E8.5 pregnant
Structure Level Pattern Image Note
TS28: corpus luteum Very strong 1D

Specimen 1E: postnatal adult (more )
Note: E14.5 pregnant
Structure Level Pattern Image Note
TS28: corpus luteum Very strong 1E

Specimen 1G: postnatal adult (more )
Note: E19 pregnant
Structure Level Pattern Image Note
TS28: corpus luteum Present 1G Reduced expression, or occasionally missing (data not shown).

Specimen 1I: postnatal adult (more )
Note: nonpregnant
Structure Level Pattern Image Note
TS28: corpus luteum Strong Regionally restricted 1I Only some corpus lutea (active corpus luteum) were positive.

Specimen 1J: postnatal adult (more )
Note: E5.5 pregnant
Structure Level Pattern Image Note
TS28: corpus luteum Strong Regionally restricted 1J Only some corpus lutea (active corpus luteum) were positive.

Specimen 1K: postnatal adult (more )
Note: E8.5 pregnant
Structure Level Pattern Image Note
TS28: corpus luteum Very strong Regionally restricted 1K Only some corpus lutea (active corpus luteum) were positive.

Specimen 1L: postnatal adult (more )
Note: E14.5 pregnant
Structure Level Pattern Image Note
TS28: corpus luteum Very strong 1L Expressed in all large corpus lutea. No expression in a few small ones whose luteolysis and involution had further progressed (not shown).

Specimen 2A: postnatal adult (more )
Note: E5.5 pregnant
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 2A Expressed in the stromal cells surrounding the implantation site, on the antimesometrial side. Expressed in the inner zone of decidualization.

Specimen 2D: postnatal adult (more )
Note: E5.5 pregnant
Structure Level Pattern Image Note
TS28: decidua Strong Regionally restricted 2D Expressed in the stromal cells surrounding the implantation site, on the antimesometrial side. High expression in the inner zone and low expression in the outer zone of decidualization.

Specimen 2F: postnatal adult (more )
Note: E5.5 pregnant
Structure Level Pattern Image Note
TS28: decidua Weak Regionally restricted 2F Low expression in the outer zone of the decidual reaction. No expression in the stromal edema.

Specimen 2H: postnatal adult (more )
Note: E8 pregnant
Structure Level Pattern Image Note
TS28: decidua capsularis Present 2H
TS28: decidua Present Regionally restricted 2H Expressed in the mesometrial decidual layer.

Specimen 2H embryo: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: trophoblast giant cell Absent 2H

Specimen 2J: postnatal adult (more )
Note: E9.5 pregnant
Structure Level Pattern Image Note
TS28: decidua capsularis Strong 2J Expression was particularly high. No expression in the mesometrial decidual layer at E9 (not shown).

Specimen 2J embryo: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Absent 2J

Specimen 3B: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: chorioallantoic placenta Present Regionally restricted 3B Expressed in the spongy or basal layer.
TS14: spongiotrophoblast Present 3B Limited to the spongiotrophoblast layer of the junctional zone.
TS14: trophoblast giant cell Absent 3B

Specimen 3C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spongiotrophoblast Present 3C
TS20: trophoblast giant cell Absent 3C

Specimen 3E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: junctional zone Strong Regionally restricted 3E Expressed in spongiotrophoblasts at the junctional zone and in the spongiotrophoblast pegs within the labyrinth region.
TS22: labyrinthine zone Strong Regionally restricted 3E Expressed in spongiotrophoblasts at the junctional zone and in the spongiotrophoblast pegs within the labyrinth region.
TS22: spongiotrophoblast Strong Regionally restricted 3E Expressed in spongiotrophoblasts at the junctional zone and in the spongiotrophoblast pegs within the labyrinth region.

Specimen 3I: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: spongiotrophoblast Strong Regionally restricted 3I Expressed in abundant spongiotrophoblasts in the peripheral region, and the region of spongiotrophoblasts that narrowed to a few cell layers between the decidual and labyrinth zones.

Specimen 3K: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: labyrinthine zone Present 3K Decreased (arrowheads) remarkably from that on E17.5.

Specimen not shown: postnatal adult (more )
Note: E4.5 pregnant
Structure Level Pattern Image Note
TS28: corpus luteum Strong
TS28: uterus Absent

Specimen not shown: postnatal adult (more )
Note: nonpregnant
Structure Level Pattern Image Note
TS28: uterus Absent

Specimen not shown: postnatal adult (more )
Note: E5.5 or E6.5 pregnant
Structure Level Pattern Image Note
TS28: myometrium Absent
TS28: uterine gland Absent

Specimen not shown: postnatal adult (more )
Note: E12.5 pregnant
Structure Level Pattern Image Note
TS28: decidua Absent After E9.5, expression gradually disappeared and could no longer be detected in the remnants of the deteriorating antimesometrial decidual layer on E12.5.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory