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Gene Expression Data
Assay Details
Assay
Reference: J:299191 Kitazawa M, et al., Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development. 2020 Sep 2;147(21):dev185918
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7643781
Gene symbol: Rtl1
Gene name: retrotransposon Gaglike 1
Antibody: Anti-Rtl1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to alkaline phosphatase
Results
Specimen 1B Pat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Fixed in Super Fix. Deletion upon paternal transmission.
Structure Level Pattern Image Note
TS27: intercostal muscle Absent 1B Pat-Rtl1 delta top , 1B Pat-Rtl1 delta bottom The mice with the deletion upon paternal transmission exhibited a loss of Rtl1 expression.
TS27: heart Absent 1B Pat-Rtl1 delta top
Specimen 1B WT(p): postnatal newborn (more )
Note: Fixed in Super Fix.
Structure Level Pattern Image Note
TS27: intercostal muscle Present Regionally restricted 1B WT (p) bottom , 1B WT (p) top Signal was observed around and along the muscle fibers.
TS27: heart Absent 1B WT (p) top
Specimen 1B WT(m): postnatal newborn (more )
Note: Fixed in Super Fix.
Structure Level Pattern Image Note
TS27: intercostal muscle Present Regionally restricted 1B WT (m) top , 1B WT (m) bottom Signal was observed around and along the muscle fibers.
TS27: heart Absent 1B WT (m) top
Specimen 1B Mat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Fixed in Super Fix. Deletion upon maternal transmission.
Structure Level Pattern Image Note
TS27: intercostal muscle Present Regionally restricted 1B Mat-Rtl1 delta top , 1B Mat-Rtl1 delta bottom Mice with maternal transmission exhibited overexpression of the paternal Rtl1 allele because of a loss of expression of most of the maternal microRNAs.
TS27: heart Absent 1B Mat-Rtl1 delta top
Specimen S5 Pat-Rtl1 delta embryo: embryonic day 14.5; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Fixed in Super Fix. Deletion upon paternal transmission.
Structure Level Pattern Image Note
TS22: muscle tissue Absent S5_Pat-Rtl1 delta top
Specimen S5 WT(p) embryo: embryonic day 14.5 (more )
Note: Fixed in Super Fix.
Structure Level Pattern Image Note
TS22: muscle tissue Present Regionally restricted S5_WT (p) top Expression was detected in fetal myofibers.
Specimen S5 WT(m) embryo: embryonic day 14.5 (more )
Note: Fixed in Super Fix.
Structure Level Pattern Image Note
TS22: muscle tissue Present Regionally restricted S5_WT (m) top Expression was detected in fetal myofibers.
Specimen S5 Mat-Rtl1 delta embryo: embryonic day 14.5; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Fixed in Super Fix. Deletion upon maternal transmission.
Structure Level Pattern Image Note
TS22: muscle tissue Present Regionally restricted S5_Mat-Rtl1 delta top Expression was detected in fetal myofibers.
Specimen S5 Pat-Rtl1 delta intercostal myotubes: embryonic day 14.5; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Fixed in Super Fix. Deletion upon paternal transmission.
Structure Level Pattern Image Note
TS22: intercostal muscle Absent S5_Pat-Rtl1 delta bottom
Specimen S5 WT(p) intercostal myotubes: embryonic day 14.5 (more )
Note: Fixed in Super Fix.
Structure Level Pattern Image Note
TS22: intercostal muscle Present Regionally restricted S5_WT (p) bottom Expression was detected in fetal myofibers.
Specimen S5 WT(m) intercostal myotubes: embryonic day 14.5 (more )
Note: Fixed in Super Fix.
Structure Level Pattern Image Note
TS22: intercostal muscle Present Regionally restricted S5_WT (m) bottom Expression was detected in fetal myofibers.
Specimen S5 Mat-Rtl1 delta intercostal myotubes: embryonic day 14.5; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Fixed in Super Fix. Deletion upon maternal transmission.
Structure Level Pattern Image Note
TS22: intercostal muscle Present Regionally restricted S5_Mat-Rtl1 delta bottom Expression was detected in fetal myofibers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory