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Gene Expression Data
Assay Details
Assay
Reference: J:43652 Deiner MS, et al., Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia. Neuron. 1997 Sep;19(3):575-89
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7643159
Gene symbol: Ntn1
Gene name: netrin 1
Antibody: anti-netrin
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 1b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: optic fissure Present Regionally restricted 1b Expression localized to cells along optic fissure and optic stalk.
TS19: optic stalk Present Regionally restricted 1b Expression localized to cells along optic fissure and optic stalk.
Specimen 1c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: optic disc Present Regionally restricted 1c Expression in two triangular-shaped groups of cells flanking retinal ganglion cell (RGC) axons exiting through disc.
Specimen 1h: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: optic disc Present Regionally restricted 1h Authors report expression in a pattern reminiscent of glial cell processes.
Specimen 1i: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain floor plate Strong 1i Expression level in hindbrain floor plate higher than in the eye.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory