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Bdnfem1(cre)Shenw
Endonuclease-mediated Allele Detail
Summary
Symbol: Bdnfem1(cre)Shenw
Name: brain derived neurotrophic factor; endonuclease-mediated mutation 1, Wei L Shen
MGI ID: MGI:7642253
Synonyms: BDNF-IRES-Cre
Gene: Bdnf  Location: Chr2:109505045-109557352 bp, + strand  Genetic Position: Chr2, 56.63 cM
Alliance: Bdnfem1(cre)Shenw page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Bdnfem1(cre)Shenw expression driven by 1 gene
 
Mutation detailsBDNF-IRES-Cre was generated by inserting an IRES-Cre sequence to the 3 UTR of BDNF coding exon through CRISPR genome editing. (J:348616)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Bdnf (mouse)
Summary of all recombinase alleles driven by Bdnf.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bdnf Mutation:  42 strains or lines available
References
Original:  J:348616 Luo F, et al., Whole-brain patterns of the presynaptic inputs and axonal projections of BDNF neurons in the paraventricular nucleus. J Genet Genomics. 2019 Jan 20;46(1):31-40
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory