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Gene Expression Data
Assay Details
Assay
Reference: J:40783 Komori T, et al., Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell. 1997 May 30;89(5):755-64
Assay type: RNA in situ
MGI Accession ID: MGI:7642184
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Cbfa1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: embryo Present 4A
Specimen 4C: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: radius osteoblast Strong 4C Stronger expression in osteoblasts than in chondrocytes.
TS26: radius chondrocyte Present 4C Stronger expression in osteoblasts than in chondrocytes.
TS26: radius osteoclast Absent 4C No significant expression in osteoclasts.
Specimen 4D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: chondrocranium Present 4D
Specimen 4E: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: thymus thymocyte Present 4E
Specimen 4F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: tendon Present 4F
Specimen 4G: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: vibrissa follicle fibroblast of dermis Weak 4G Weak expression in dermis.
Specimen d18.5 not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brain Absent
TS26: gut Absent
TS26: heart Absent
TS26: liver Absent
TS26: lung Absent
TS26: muscle tissue Absent
Specimen d10.5 not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb Trace Regionally restricted Faint expression with no significant localization.
Specimen d12.5 not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb Trace Faint expression with no significant localization.
Specimen d13.5 not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: limb mesenchyme Present Regionally restricted Significant expression first detected at d13.5 in region surrounding cartilaginous condensations and in tendon.
Specimen d14.5 not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: limb mesenchyme Present Regionally restricted Expression more evident at d14.5 in perichondrial region and tendon.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory