Gene Expression Data
Assay Details
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Assay
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Reference:
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J:40768
Srivastava D, et al., Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat Genet. 1997 Jun;16(2):154-60
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7641839
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Gene symbol:
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Hand1
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Gene name:
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heart and neural crest derivatives expressed 1
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Probe:
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eHAND probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
1d:
embryonic day 7.75
(more  )
Specimen
1d:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 7.75
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: heart |
Present |
Regionally restricted |
1d
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Expression throughout precardiogenic mesoderm, symmetric along left-right axis of embryo
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Specimen
1e:
embryonic day 8.0
(more )
Specimen
1e:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: bulbus cordis rostral half |
Present |
Regionally restricted |
1e
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Expression restricted to anterior (rostral) and posterior (caudal) segments of straight heart tube, fated to form conotruncus and left ventricle. No expression in intervening right ventricle-forming region. Symmetric expression along left-right axis of caudal heart tube.
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| TS12: primitive ventricle |
Present |
Regionally restricted |
1e
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Expression restricted to anterior (rostral) and posterior (caudal) segments of straight heart tube, fated to form conotruncus and left ventricle. No expression in intervening right ventricle-forming region. Symmetric expression along left-right axis of caudal heart tube.
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| TS12: lateral plate mesoderm |
Present |
Regionally restricted |
1e
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Symmetric expression along left-right axis of lateral mesoderm.
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Specimen
1f:
embryonic day 10.0
(more )
Specimen
1f:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5a:
embryonic day 9.5
(more )
Specimen
5a:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5b:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Hand2tm1Dsr/Hand2tm1Dsr
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: bulbus cordis rostral half |
Present |
Regionally restricted |
5b
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Robust ventricular and mesodermal expression, contiguous from conotruncus to single ventricle without usual gap of expression in right ventricle.
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| TS15: mesenchyme derived from lateral plate |
Present |
Regionally restricted |
5b
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Robust ventricular and mesodermal expression, contiguous from conotruncus to single ventricle without usual gap of expression in right ventricle.
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| TS15: primitive ventricle |
Present |
Regionally restricted |
5b
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Robust ventricular and mesodermal expression, contiguous from conotruncus to single ventricle without usual gap of expression in right ventricle.
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