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Gene Expression Data
Assay Details
Assay
Reference: J:40768 Srivastava D, et al., Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat Genet. 1997 Jun;16(2):154-60
Assay type: RNA in situ
MGI Accession ID: MGI:7641838
Gene symbol: Hand2
Gene name: heart and neural crest derivatives expressed 2
Probe: dHAND probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1a: embryonic day 7.75 (more )
Structure Level Pattern Image Note
TS11: heart Present Widespread 1a Expression throughout precardiogenic mesoderm.
Specimen 1b: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: bulbus cordis rostral half Present Regionally restricted 1b Expression maintained throughout straight heart tube, but becomes more restricted to conotruncus and future right ventricle as heart tube forms a loop.
TS12: primitive ventricle Present Regionally restricted 1b Expression maintained throughout straight heart tube, but becomes more restricted to conotruncus and future right ventricle as heart tube forms a loop.
Specimen 1c: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Present Regionally restricted 1c Expression restricted to right side of heart
TS15: mesenchyme derived from lateral plate Present 1c Expression in lateral mesoderm.
TS15: branchial arch Present 1c Expression in neural-crest derived branchial arches.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory