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Gene Expression Data
Assay Details
Assay
Reference: J:306057 Guo L, et al., Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling. Nat Commun. 2021 Apr 6;12(1):2046
Assay type: RNA in situ
MGI Accession ID: MGI:7639872
Gene symbol: Tmem53
Gene name: transmembrane protein 53
Probe: Tmem53 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4a (upper): embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: chondrocranium Present 4a Antisense (upper)
Specimen 4a (lower): postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: chondrocranium Present 4a Antisense (lower)
Specimen S16a: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: forelimb long bone Present Regionally restricted S16a
TS26: epiphyseal plate Present Regionally restricted S16a Expression in proliferative and pre-hypertrophic zones of growth plate.
TS26: epiphyseal plate proliferative zone Present S16a
TS26: periosteum Present Regionally restricted S16a Expression in periosteal zone of tubular bones.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory