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Gene Expression Data
Assay Details
Assay
Reference: J:327416 Pailles M, et al., H3K27me3 at pericentromeric heterochromatin is a defining feature of the early mouse blastocyst. Sci Rep. 2022 Aug 16;12(1):13908
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7639749
Gene symbol: Ezh2
Gene name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Antibody: anti-EZH2
Results
Specimen 5a 2-cell: embryonic day 1.0 (more )
Note: Double labeled: red - Ezh2; green - DAPI.
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present Regionally restricted 5a 2-cell EZH2 , 5a 2-cell (merged) Expression localized around chromocenters from 2-cell up to 16-cell stage.
Specimen 5a 4-cell: embryonic day 2.0 (more )
Note: Double labeled: red - Ezh2; green - DAPI.
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present Regionally restricted 5a 4-cell EZH2 , 5a 4-cell (merged) Expression localized around chromocenters from 2-cell up to 16-cell stage.
Specimen 5a 8-cell: embryonic day 2.5 (more )
Note: Double labeled: red - Ezh2; green - DAPI.
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present Regionally restricted 5a 8-cell (merged) , 5a 8-cell EZH2 Expression localized around chromocenters from 2-cell up to 16-cell stage.
Specimen 5a 16-cell: embryonic day 3.0 (more )
Note: Double labeled: red - Ezh2; green - DAPI.
Structure Level Pattern Image Note
TS3: compacted morula Present 5a 16-cell EZH2 , 5a 16-cell (merged) Expression localized around chromocenters from 2-cell up to 16-cell stage.
Specimen 5c E3.5: embryonic day 3.5 (more )
Note: Double labeled: red - Ezh2; green - DAPI.
Structure Level Pattern Image Note
TS4: blastocyst Present Regionally restricted 5c E3.5 (merged) , 5c E3.5 EZH2 Expression becomes less specifically localized around chromocenters in all cells of blastocyst.
Specimen 5c E4.0: embryonic day 4.0 (more )
Note: Double labeled: red - Ezh2; green - DAPI.
Structure Level Pattern Image Note
TS6: blastocyst Present Diffuse 5c E4.0 (merged) , 5c E4.0 EZH2 Expression remains diffuse afterwards.
Specimen 5c E5.5: embryonic day 5.5 (more )
Note: Double labeled: red - Ezh2; green - DAPI.
Structure Level Pattern Image Note
TS7: egg cylinder Present Diffuse 5c E5.5 EZH2 , 5c E5.5 (merged) Expression remains diffuse afterwards.
Specimen S5a EZH2: embryonic day 3.5 (more )
Note: Double labeled: red - Ezh2; green - DAPI.
Structure Level Pattern Image Note
TS4: blastocyst Present Regionally restricted S5a EZH2 Expression becomes less specifically localized around chromocenters in all cells of blastocyst.
Specimen S5b EZH2: embryonic day 4.0 (more )
Note: Double labeled: red - Ezh2; green - DAPI.
Structure Level Pattern Image Note
TS6: blastocyst Present Diffuse S5b EZH2 Expression remains diffuse afterwards.
Specimen S5c EZH2: embryonic day 5.5 (more )
Note: Double labeled: red - Ezh2; green - DAPI.
Structure Level Pattern Image Note
TS7: egg cylinder Present Diffuse S5c EZH2 Expression remains diffuse afterwards.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory