About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:83508 Shibaguchi T, et al., Expression and role of Lhx8 in murine tooth development. Arch Histol Cytol. 2003 Mar;66(1):95-108
Assay type: RNA in situ
MGI Accession ID: MGI:7627119
Gene symbol: Lhx8
Gene name: LIM homeobox protein 8
Probe: Lhx8 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1a/b: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: molar mesenchyme Strong 1a/b
TS21: jaw mesenchyme Strong Regionally restricted 1a/b Expressed in the mesenchyme beneath the oral epithelium around the tooth germs.

Specimen 1c/d: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar dental papilla Present 1c/d
TS22: dental sac Present Regionally restricted 1c/d Slightly expressed in the dental sac of the cap stage tooth germs.
TS22: jaw mesenchyme Weak Regionally restricted 1c/d Expression in the mesenchyme beneath the oral epithelium around the tooth germs was weak.

Specimen 1e/f: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lower jaw molar dental papilla Present 1e/f Expression was downregulated.
TS24: jaw mesenchyme Trace Regionally restricted 1e/f Expression was hardly recognized in the mesenchyme beneath the oral epithelium around the tooth germs.

Specimen 1g/h: embryonic day 18.5 (more )
Note: late bell stage of the mandibular 1st molar
Structure Level Pattern Image Note
TS26: lower jaw molar dental papilla Present Regionally restricted 1g/h No expression in the late bell stage tooth germs of mandibular first molars, but it was clearly detected in the mandibular second molar (early bell stage, 1j).
TS26: lower jaw 1st molar Absent 1g/h

Specimen 1i/j: embryonic day 18.5 (more )
Note: cap to early bell stage of the mandibular 2nd molar
Structure Level Pattern Image Note
TS26: lower jaw molar dental papilla Present Regionally restricted 1i/j Clearly detected in the mandibular second molar.
TS26: lower jaw 2nd molar Present Regionally restricted 1i/j Expressed in the dental papilla.

Specimen not shown: postnatal day 0.5 (more )
Structure Level Pattern Image Note
TS27: lower jaw 1st molar Absent There was no expression in the tooth germs of the mandibular first molars.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory