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Gene Expression Data
Assay Details
Assay
Reference: J:177282 Vissers LE, et al., Heterozygous mutations of FREM1 are associated with an increased risk of isolated metopic craniosynostosis in humans and mice. PLoS Genet. 2011 Sep;7(9):e1002278
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7627042
Gene symbol: Frem1
Gene name: Fras1 related extracellular matrix protein 1
Antibody: anti-Frem1
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2C: postnatal day 0 (more )
Note: Double labeled: red - Frem1; green - Nid1 (assay MGI:7627043).
Structure Level Pattern Image Note
TS27: frontal bone Present Regionally restricted 2D' , 2D , 2C There is fibrillar pericranial expression overlying the developing frontal bones.
TS27: brain dura mater Present Regionally restricted 2D' , 2C , 2D Expression is in the dura mater underlying the frontal bones.
Specimen 2E: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: frontal suture mesenchyme Weak Regionally restricted 2E , 2E' Expression is diffuse in the suture mesenchyme at the medial edge of the frontal bones.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory